日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Titin's P-zone domains A164-167 are essential for thick filament structural arrangement.

肌联蛋白的 P 区结构域 A164-167 对粗丝的结构排列至关重要。

Hoover Browne Catherine, Han Seong-Won, Farman Gerrie P, Smith John E, Kolb Justin, Gohlke Jochen, Langlais Paul R, Tonino Paola, Methawasin Mei, van der Pijl Robbert, Granzier Henk

Importance of N2BA Titin in Maintaining Cardiac Homeostasis and Its Role in Dilated Cardiomyopathy

N2BA 肌联蛋白在维持心脏稳态中的重要性及其在扩张型心肌病中的作用

van der Pijl, Robbert; Nusayr, Eyad; Strom, Joshua; Slater, Rebecca; Gohlke, Jochen; Hourani, Zaynab; Saripalli, Chandra; Kolb, Justin; Hermanson, Kyra; Brynnel, Odhin; Smith, John E 3rd; Labeit, Siegfried; Methawasin, Mei; Granzier, Henk

Generation of a novel mouse model of nemaline myopathy due to recurrent NEB exon 55 deletion.

构建了一种由复发性 NEB 外显子 55 缺失引起的线状肌病的新型小鼠模型

Coulson Zachary, Kolb Justin, Sabha Nesrin, Karimi Esmat, Hourani Zaynab, Ottenheijm Coen, Granzier Henk, Dowling James J

Glycerol storage increases passive stiffness of muscle fibers through effects on titin extensibility

甘油储存通过影响肌联蛋白的伸展性来增加肌肉纤维的被动刚度。

Han, Seong-Won; Kolb, Justin; Farman, Gerrie P; Gohlke, Jochen; Granzier, Henk L

Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects

对患者中NEB致病变异的特征分析揭示了新的线状肌病疾病机制和omecamtiv mecarbil的作用机制。

Karimi, Esmat; Gohlke, Jochen; van der Borgh, Mila; Lindqvist, Johan; Hourani, Zaynab; Kolb, Justin; Cossette, Stacy; Lawlor, Michael W; Ottenheijm, Coen; Granzier, Henk

Omecamtiv mecarbil lowers the contractile deficit in a mouse model of nebulin-based nemaline myopathy

Omecamtiv mecarbil 可降低小鼠模型中基于尼布林的线状肌病的收缩功能障碍。

Lindqvist, Johan; Lee, Eun-Jeong; Karimi, Esmat; Kolb, Justin; Granzier, Henk