Komba Mitsuhiro相关文献与解析，生知库 | 链接生命科学的每一步

Denroche, Heather C; Ng, Victoria; Velghe, Jane; Suen, Imelda; Stanley, Liam; Nackiewicz, Dominika; Komba, Mitsuhiro; Dai, Derek L; Soukhatcheva, Galina; Chen, Sam; Verchere, C Bruce

代谢

糖尿病

免疫/内分泌

发表日期：2026

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Manipulation of Gene Expression in Mouse Pancreas via Intraductal Delivery of Adeno-Associated Viral Vectors

通过导管内递送腺相关病毒载体调控小鼠胰腺基因表达

期刊:Oncology Letters

影响因子:2.2

doi:10.3892/ol.2016.4420

Liu, Lei; Zhu, Yingqiao; Wang, Dongxuan; Yang, Changbin; Zhang, Q I; Li, Xiukun; Bai, Yang; Soukhatcheva, Galina; Stanley, Liam; Dai, Lei; Komba, Mitsuhiro; Andriiets, Volodymyr; Johnson, James D; Verchere, Bruce C; Chen, Yi-Chun

Manipulation of Gene Expression in Mouse Pancreas via Intraductal Delivery of Adeno-Associated Viral Vectors

通过导管内递送腺相关病毒载体调控小鼠胰腺基因表达

期刊:Bio-protocol

影响因子:1.1

doi:10.21769/BioProtoc.5657

Soukhatcheva, Galina; Stanley, Liam; Dai, Lei; Komba, Mitsuhiro; Andriiets, Volodymyr; Johnson, James D; Verchere, Bruce C; Chen, Yi-Chun

Peptidylglycine alpha-amidating monooxygenase is important in mice for beta-cell cilia formation and insulin secretion but promotes diabetes risk through beta-cell independent mechanisms.

肽酰甘氨酸α-酰胺化单加氧酶在小鼠中对β细胞纤毛形成和胰岛素分泌很重要，但通过非β细胞机制促进糖尿病风险

期刊:Molecular Metabolism

影响因子:6.6

doi:10.1016/j.molmet.2025.102123

Chen Yi-Chun, BÃ¤ck Nils E, Zhen Jenicia, Xiong Lena, Komba Mitsuhiro, Gloyn Anna L, MacDonald Patrick E, Mains Richard E, Eipper Betty A, Verchere C Bruce

Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice

β细胞中羧肽酶E的缺失会破坏胰岛素原的加工过程，但不会导致小鼠自发性糖尿病的发生。

期刊:Diabetes

影响因子:7.5

doi:10.2337/db22-0945

Chen, Yi-Chun; Taylor, Austin J; Fulcher, James M; Swensen, Adam C; Dai, Xiao-Qing; Komba, Mitsuhiro; Wrightson, Kenzie L C; Fok, Kenny; Patterson, Annette E; Klein Geltink, Ramon I; MacDonald, Patrick E; Qian, Wei-Jun; Verchere, C Bruce

Islet amyloid disrupts MHC class II antigen presentation and delays autoimmune diabetes in NOD mice

胰岛淀粉样蛋白会破坏MHC II类抗原呈递，并延缓NOD小鼠自身免疫性糖尿病的发生。

Manipulation of Gene Expression in Mouse Pancreas via Intraductal Delivery of Adeno-Associated Viral Vectors

通过导管内递送腺相关病毒载体调控小鼠胰腺基因表达

Manipulation of Gene Expression in Mouse Pancreas via Intraductal Delivery of Adeno-Associated Viral Vectors

通过导管内递送腺相关病毒载体调控小鼠胰腺基因表达

Peptidylglycine alpha-amidating monooxygenase is important in mice for beta-cell cilia formation and insulin secretion but promotes diabetes risk through beta-cell independent mechanisms.

肽酰甘氨酸α-酰胺化单加氧酶在小鼠中对β细胞纤毛形成和胰岛素分泌很重要，但通过非β细胞机制促进糖尿病风险

Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice

β细胞中羧肽酶E的缺失会破坏胰岛素原的加工过程，但不会导致小鼠自发性糖尿病的发生。