日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ELP1, the Gene Mutated in Familial Dysautonomia, Is Required for Normal Enteric Nervous System Development and Maintenance and for Gut Epithelium Homeostasis.

ELP1 基因在家族性自主神经功能障碍中发生突变,它是正常肠神经系统发育和维持以及肠道上皮稳态所必需的

Chaverra Marta, Cheney Alexandra M, Scheel Alpha, Miller Alessa, George Lynn, Schultz Anastasia, Henningsen Katelyn, Kominsky Douglas, Walk Heather, Kennedy William R, Kaufmann Horacio, Walk Seth, Copié Valérie, Lefcort Frances

Amino Acid Trp: The Far Out Impacts of Host and Commensal Tryptophan Metabolism

氨基酸色氨酸:宿主和共生菌色氨酸代谢的深远影响

Grifka-Walk, Heather M; Jenkins, Brittany R; Kominsky, Douglas J

Oral vitamin B(12) supplement is delivered to the distal gut, altering the corrinoid profile and selectively depleting Bacteroides in C57BL/6 mice

口服维生素B12补充剂可输送至远端肠道,从而改变C57BL/6小鼠肠道内的类咕啉谱并选择性地减少拟杆菌属细菌。

Kelly, Caleb J; Alexeev, Erica E; Farb, Linda; Vickery, Thad W; Zheng, Leon; Eric L, Campbell; Kitzenberg, David A; Battista, Kayla D; Kominsky, Douglas J; Robertson, Charles E; Frank, Daniel N; Stabler, Sally P; Colgan, Sean P

Microbial-Derived Butyrate Promotes Epithelial Barrier Function through IL-10 Receptor-Dependent Repression of Claudin-2.

微生物来源的丁酸盐通过 IL-10 受体依赖性抑制 Claudin-2 来促进上皮屏障功能

Zheng Leon, Kelly Caleb J, Battista Kayla D, Schaefer Rachel, Lanis Jordi M, Alexeev Erica E, Wang Ruth X, Onyiah Joseph C, Kominsky Douglas J, Colgan Sean P

Intestinal Epithelial Ecto-5'-Nucleotidase (CD73) Regulates Intestinal Colonization and Infection by Nontyphoidal Salmonella

肠道上皮细胞外-5'-核苷酸酶(CD73)调节非伤寒沙门氏菌的肠道定植和感染

Kao, Daniel J; Saeedi, Bejan J; Kitzenberg, David; Burney, Krista M; Dobrinskikh, Evgenia; Battista, Kayla D; Vázquez-Torres, Andrés; Colgan, Sean P; Kominsky, Douglas J

Hypoxia and Mucosal Inflammation

缺氧和黏膜炎症

Colgan, Sean P; Campbell, Eric L; Kominsky, Douglas J

Perturbation of neddylation-dependent NF-κB responses in the intestinal epithelium drives apoptosis and inhibits resolution of mucosal inflammation

肠上皮细胞中NEDDylation依赖性NF-κB反应的扰动会驱动细胞凋亡并抑制黏膜炎症的消退。

Ehrentraut, Stefan F; Curtis, Valerie F; Wang, Ruth X; Saeedi, Bejan J; Ehrentraut, Heidi; Onyiah, Joseph C; Kelly, Caleb J; Campbell, Eric L; Glover, Louise E; Kominsky, Douglas J; Colgan, Sean P

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

肠道菌群来源的短链脂肪酸与肠上皮细胞HIF之间的相互作用增强组织屏障功能

Kelly, Caleb J; Zheng, Leon; Campbell, Eric L; Saeedi, Bejan; Scholz, Carsten C; Bayless, Amanda J; Wilson, Kelly E; Glover, Louise E; Kominsky, Douglas J; Magnuson, Aaron; Weir, Tiffany L; Ehrentraut, Stefan F; Pickel, Christina; Kuhn, Kristine A; Lanis, Jordi M; Nguyen, Vu; Taylor, Cormac T; Colgan, Sean P

Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses

通过抑制 Cullin-2 的 neddylation 修饰来稳定 HIF,对黏膜炎症反应具有保护作用。

Curtis, Valerie F; Ehrentraut, Stefan F; Campbell, Eric L; Glover, Louise E; Bayless, Amanda; Kelly, Caleb J; Kominsky, Douglas J; Colgan, Sean P

IFN-γ-mediated induction of an apical IL-10 receptor on polarized intestinal epithelia.

IFN-γ介导的极化肠上皮细胞顶端IL-10受体的诱导

Kominsky Douglas J, Campbell Eric L, Ehrentraut Stefan F, Wilson Kelly E, Kelly Caleb J, Glover Louise E, Collins Colm B, Bayless Amanda J, Saeedi Bejan, Dobrinskikh Evgenia, Bowers Brittelle E, MacManus Christopher F, Müller Werner, Colgan Sean P, Bruder Dunja