Konc相关文献与解析，生知库 | 链接生命科学的每一步

Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform

基于 Simoa 平台的超灵敏蛋白聚集体定量检测方法用于神经退行性疾病的研究

doi:10.1021/acs.analchem.4c04188

Dorothea Böken ，Zengjie Xia ，Jeff Y L Lam ，Emre Fertan ，Yunzhao Wu ，Elizabeth A English ，Juraj Konc ，Florence Layburn ，Gonçalo J L Bernardes ，Henrik Zetterberg ，Matthew R Cheetham ，David Klenerman

神经科学

发表日期：2025

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Correction to "Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform"

对“基于 Simoa 平台的神经退行性疾病超灵敏蛋白聚集体定量分析”一文的更正

期刊:Analytical Chemistry

影响因子:6.7

doi:10.1021/acs.analchem.5c00703

Böken, Dorothea; Xia, Zengjie; Lam, Jeff Y L; Fertan, Emre; Wu, Yunzhao; English, Elizabeth A; Konc, Juraj; Layburn, Florence; Bernardes, Gonçalo J L; Zetterberg, Henrik; Cheetham, Matthew R; Klenerman, David

神经科学

发表日期：2025

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Small-molecule inhibitors of 6-phosphofructo-1-kinase simultaneously suppress lactate and superoxide generation in cancer cells.

6-磷酸果糖-1-激酶的小分子抑制剂可同时抑制癌细胞中乳酸和超氧化物的产生

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0321998

LeÅ¡nik Samo, Konc Janez, Vodopivec Tina, Äamernik Katja, Karolina Potokar UrÅ¡ka, LegiÅ¡a Matic

细胞生物学

发表日期：2025

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Identification of potential human targets for epigallocatechin gallate through a novel protein binding site screening approach

通过一种新型蛋白质结合位点筛选方法鉴定表没食子儿茶素没食子酸酯的潜在人类靶点

期刊:Journal of Molecular Modeling

影响因子:2.5

doi:10.1007/s00894-025-06410-y

Hirci, Jernej; Škufca, Sandra; Kunej, Tanja; Janežič, Dušanka; Konc, Janez

发表日期：2025

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Whole genome sequencing of mouse lines divergently selected for fatness (FLI) and leanness (FHI) revealed several genetic variants as candidates for novel obesity genes

对肥胖（FLI）和瘦弱（FHI）两种不同选择的小鼠品系进行全基因组测序，揭示了几个可能与新型肥胖基因相关的遗传变异。

期刊:Genes & Genomics

影响因子:1.7

doi:10.1007/s13258-024-01507-9

Šimon, Martin; Mikec, Špela; Atanur, Santosh S; Konc, Janez; Morton, Nicholas M; Horvat, Simon; Kunej, Tanja

Genome-wide screening for genetic variants in polyadenylation signal (PAS) sites in mouse selection lines for fatness and leanness

对肥胖和瘦弱小鼠选择系中多聚腺苷酸化信号（PAS）位点的遗传变异进行全基因组筛查

期刊:Mammalian Genome

影响因子:2.7

doi:10.1007/s00335-022-09967-8

Šimon, Martin; Mikec, Špela; Morton, Nicholas M; Atanur, Santosh S; Konc, Janez; Horvat, Simon; Kunej, Tanja

A small bacteriophage protein determines the hierarchy over co-residential jumbo phage in Bacillus thuringiensis serovar israelensis

一种小型噬菌体蛋白决定了苏云金芽孢杆菌以色列血清型中共存巨型噬菌体的等级

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-022-04238-3

Anja Pavlin #, Anže Lovše #, Gregor Bajc, Jan Otoničar, Amela Kujović, Živa Lengar, Ion Gutierrez-Aguirre, Rok Kostanjšek, Janez Konc, Nadine Fornelos, Matej Butala

免疫

发表日期：2022

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Protein binding sites for drug design

用于药物设计的蛋白质结合位点

期刊:Biophysical Reviews

影响因子:3.7

doi:10.1007/s12551-022-01028-3

Konc, Janez; Janežič, Dušanka

发表日期：2022

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Mechanistic Insights into Side Effects of Troglitazone and Rosiglitazone Using a Novel Inverse Molecular Docking Protocol

利用新型反向分子对接方案深入研究曲格列酮和罗格列酮的副作用机制

期刊:Pharmaceutics

影响因子:5.5

doi:10.3390/pharmaceutics13030315

Kores, Katarina; Konc, Janez; Bren, Urban

发表日期：2021

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Targeted Protein Modification with an Antibody-Based System

利用抗体系统进行靶向蛋白质修饰

Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform

基于 Simoa 平台的超灵敏蛋白聚集体定量检测方法用于神经退行性疾病的研究

Correction to "Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform"

对“基于 Simoa 平台的神经退行性疾病超灵敏蛋白聚集体定量分析”一文的更正

Small-molecule inhibitors of 6-phosphofructo-1-kinase simultaneously suppress lactate and superoxide generation in cancer cells.

6-磷酸果糖-1-激酶的小分子抑制剂可同时抑制癌细胞中乳酸和超氧化物的产生

Identification of potential human targets for epigallocatechin gallate through a novel protein binding site screening approach

通过一种新型蛋白质结合位点筛选方法鉴定表没食子儿茶素没食子酸酯的潜在人类靶点

Whole genome sequencing of mouse lines divergently selected for fatness (FLI) and leanness (FHI) revealed several genetic variants as candidates for novel obesity genes

对肥胖（FLI）和瘦弱（FHI）两种不同选择的小鼠品系进行全基因组测序，揭示了几个可能与新型肥胖基因相关的遗传变异。

Genome-wide screening for genetic variants in polyadenylation signal (PAS) sites in mouse selection lines for fatness and leanness

对肥胖和瘦弱小鼠选择系中多聚腺苷酸化信号（PAS）位点的遗传变异进行全基因组筛查

A small bacteriophage protein determines the hierarchy over co-residential jumbo phage in Bacillus thuringiensis serovar israelensis

一种小型噬菌体蛋白决定了苏云金芽孢杆菌以色列血清型中共存巨型噬菌体的等级

Protein binding sites for drug design

用于药物设计的蛋白质结合位点

Mechanistic Insights into Side Effects of Troglitazone and Rosiglitazone Using a Novel Inverse Molecular Docking Protocol

利用新型反向分子对接方案深入研究曲格列酮和罗格列酮的副作用机制