日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor

胰腺腺癌的组合筛选揭示了对包括溴结构域抑制剂加NEDDylation抑制剂在内的药物组合的敏感性

Langdon, Casey G; Platt, James T; Means, Robert E; Iyidogan, Pinar; Mamillapalli, Ramanaiah; Klein, Michael; Held, Matthew A; Lee, Jong Woo; Koo, Ja Seok; Hatzis, Christos; Hochster, Howard S; Stern, David F

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer

BATTLE-2 研究:一项针对既往接受过治疗的晚期非小细胞肺癌患者的生物标志物整合靶向治疗研究

Papadimitrakopoulou, Vassiliki; Lee, J Jack; Wistuba, Ignacio I; Tsao, Anne S; Fossella, Frank V; Kalhor, Neda; Gupta, Sanjay; Byers, Lauren Averett; Izzo, Julie G; Gettinger, Scott N; Goldberg, Sarah B; Tang, Ximing; Miller, Vincent A; Skoulidis, Ferdinandos; Gibbons, Don L; Shen, Li; Wei, Caimiao; Diao, Lixia; Peng, S Andrew; Wang, Jing; Tam, Alda L; Coombes, Kevin R; Koo, Ja Seok; Mauro, David J; Rubin, Eric H; Heymach, John V; Hong, Waun Ki; Herbst, Roy S

CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma

肿瘤细胞中CXCR2的表达是肺腺癌预后不良的因素,并促进其侵袭和转移。

Saintigny, Pierre; Massarelli, Erminia; Lin, Steven; Ahn, Young-Ho; Chen, Yulong; Goswami, Sangeeta; Erez, Baruch; O'Reilly, Michael S; Liu, Diane; Lee, J Jack; Zhang, Li; Ping, Yuan; Behrens, Carmen; Solis Soto, Luisa M; Heymach, John V; Kim, Edward S; Herbst, Roy S; Lippman, Scott M; Wistuba, Ignacio I; Hong, Waun Ki; Kurie, Jonathan M; Koo, Ja Seok

Prevention of bronchial hyperplasia by EGFR pathway inhibitors in an organotypic culture model

在类器官培养模型中,EGFR通路抑制剂可预防支气管增生

Lee, Jangsoon; Ryu, Seung-Hee; Kang, Shin Myung; Chung, Wen-Cheng; Gold, Kathryn Ann; Kim, Edward S; Hittelman, Walter N; Ki Hong, Waun; Koo, Ja Seok

Airway mucus: the good, the bad, the sticky

呼吸道黏液:有益的、有害的、粘稠的

Evans, Christopher M; Koo, Ja Seok

Cyclic AMP-responsive element binding protein- and nuclear factor-kappaB-regulated CXC chemokine gene expression in lung carcinogenesis

环磷酸腺苷反应元件结合蛋白和核因子κB调控的CXC趋化因子基因表达在肺癌发生中的作用

Sun, Hongxia; Chung, Wen-Cheng; Ryu, Seung-Hee; Ju, Zhenlin; Tran, Hai T; Kim, Edward; Kurie, Jonathan M; Koo, Ja Seok

Regulation of mucin gene expression by CREB via a nonclassical retinoic acid signaling pathway

CREB通过非经典视黄酸信号通路调控粘蛋白基因表达

Kim, Seung-Wook; Hong, Jeong Soo; Ryu, Seung-Hee; Chung, Wen-Cheng; Yoon, Joo-Heon; Koo, Ja Seok

Nonclassical action of retinoic acid on the activation of the cAMP response element-binding protein in normal human bronchial epithelial cells

视黄酸对正常人支气管上皮细胞中 cAMP 反应元件结合蛋白活化的非经典作用

Aggarwal, Sita; Kim, Seung-Wook; Cheon, Kyounga; Tabassam, Fazal H; Yoon, Joo-Heon; Koo, Ja Seok

Regulation of inducible nitric oxide synthase by rapid cellular turnover and cotranslational down-regulation by dimerization inhibitors

诱导型一氧化氮合酶的调控是通过快速的细胞周转和二聚化抑制剂的共翻译下调实现的

Kolodziejski, Pawel J; Koo, Ja-Seok; Eissa, N Tony

Ubiquitination of inducible nitric oxide synthase is required for its degradation.

诱导型一氧化氮合酶的泛素化是其降解所必需的

Kolodziejski Pawel J, Musial Aleksandra, Koo Ja-Seok, Eissa N Tony