日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud.

通过将远端肾单位与输尿管芽融合,在人类肾脏类器官中整合集合系统

Shi Min, Crouse Brittney, Sundaram Nambirajan, Pode Shakked Naomi, Thorner Konrad, King Nathaniel M, Dutta Parna, Ester Lioba, Zhang Weitao, Govindarajah Vinothini, Kopan Raphael, Cebrian Cristina, Mayhew Christopher N, Helmrath Michael A, Bonventre Joseph V, McCracken Kyle W

Defective Notch1 signaling in endothelial cells drives pathogenesis in a mouse model of Adams-Oliver syndrome

内皮细胞中Notch1信号传导缺陷驱动Adams-Oliver综合征小鼠模型的发病机制

Solano, Alyssa F; Preusse, Kristina; Cain, Brittany; Hotz, Rebecca; Gavini, Parthav; Yuan, Zhenyu; Bowen, Benjamin; Maco, Gabrielle; Neal, Hope; Gagliani, Ellen K; Ahn, Christopher; Lim, Hee-Woong; Southgate, Laura; Kovall, Rhett A; Kopan, Raphael; Gebelein, Brian

Bridging the gap of late-gestation nephrogenesis using a non-human primate model

利用非人灵长类动物模型弥合妊娠晚期肾脏发育的差距

Thakkar, Kairavee; Yarlagadda, Sunitha; Alkhudairy, Lyan; Potter, Andrew; Thorner, Konrad; Chaturvedi, Praneet; McCracken, Kyle W; Salomonis, Nathan; Kopan, Raphael; Schuh, Meredith P

Reduced Nephron Endowment in Six2-TGCtg Mice Is Due to Six3 Misexpression by Aberrant Enhancer-Promoter Interactions in the Transgene.

Six2-TGCtg 小鼠肾单位数量减少是由于转基因中异常的增强子-启动子相互作用导致 Six3 错误表达所致

Perl Alison J, Liu Han, Hass Matthew, Adhikari Nirpesh, Chaturvedi Praneet, Hu Yueh-Chiang, Jiang Rulang, Liu Yaping, Kopan Raphael

The unique functions of Runx1 in skeletal muscle maintenance and regeneration are facilitated by an ETS interaction domain

Runx1在骨骼肌维持和再生中的独特功能是由其ETS相互作用域介导的。

Yu, Meng; Thorner, Konrad; Parameswaran, Sreeja; Wei, Wei; Yu, Chuyue; Lin, Xinhua; Kopan, Raphael; Hass, Matthew R

Reduced nephron endowment in the common Six2-TGC (tg) mouse line is due to Six3 misexpression by aberrant enhancer-promoter interactions in the transgene

常见的 Six2-TGC (tg) 小鼠品系肾单位数量减少是由于转基因中异常的增强子-启动子相互作用导致 Six3 表达异常所致。

Perl, Alison J; Liu, Han; Hass, Matthew; Adhikari, Nirpesh; Chaturvedi, Praneet; Hu, Yueh-Chiang; Jiang, Rulang; Liu, Yaping; Kopan, Raphael

Regulation of nephron progenitor cell lifespan and nephron endowment

肾单位祖细胞寿命和肾单位数量的调控

Perl, Alison J; Schuh, Meredith P; Kopan, Raphael

TSLP disease-associated genetic variants combined with airway TSLP expression influence asthma risk

TSLP疾病相关基因变异与气道TSLP表达相结合,影响哮喘风险。

Murrison, Liza Bronner; Ren, Xiaomeng; Preusse, Kristina; He, Hua; Kroner, John; Chen, Xiaoting; Jenkins, Seth; Johansson, Elisabet; Biagini, Jocelyn M; Weirauch, Matthew T; Kopan, Raphael; Martin, Lisa J; Khurana Hershey, Gurjit K

Hamartin regulates cessation of mouse nephrogenesis independently of Mtor

Hamartin独立于mTOR调控小鼠肾脏发育的终止。

Volovelsky, Oded; Nguyen, Thi; Jarmas, Alison E; Combes, Alexander N; Wilson, Sean B; Little, Melissa H; Witte, David P; Brunskill, Eric W; Kopan, Raphael

The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force

经典的Notch信号通路:结构和生化层面揭示其形状、糖类和作用力

Kovall, Rhett A; Gebelein, Brian; Sprinzak, David; Kopan, Raphael