日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Direct Inhibition of RAS Reveals the Features of Oncogenic Signaling Driven by RAS G12 and Q61 Mutations.

直接抑制 RAS 揭示了由 RAS G12 和 Q61 突变驱动的致癌信号的特征

期刊:Cancer Discovery
影响因子:33.3
doi:10.1158/2159-8290.CD-24-0614
Marasco Michelangelo, Kumar Dinesh, Garcia Borrego Santiago, Seale Tessa, Maddalena Giulia, Mezzadra Riccardo, Belanger Kylie, Cole Soren, Perez Brayan, Luan Wei, Mukherjee Radha, Aricescu Ilinca, Markov Vladimir, Zhu Yuxin, Arena Sabrina, Bardelli Alberto, de Stanchina Elisa, Lowe Scott W, Burkhart Richard A, Zimmerman Jacquelyn W, Yaeger Rona, Kopetz Scott E, Rosen Neal, Misale Sandra
信号转导
肿瘤免疫
发表日期：2025
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Impact of Co-mutations and Transcriptional Signatures in Non-Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial.

KRYSTAL-1 试验中，Adagrasib 治疗非小细胞肺癌患者的共突变和转录特征的影响

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-24-2310
Negrao Marcelo V, Paula Alvaro G, Molkentine David, Hover Laura, Nilsson Monique, Vokes Natalie, Engstrom Lars, Calinisan Andrew, Briere David M, Waters Laura, Hallin Jill, Diao Lixia, Altan Mehmet, Blumenschein George R, Skoulidis Ferdinandos, Wang Jing, Kopetz Scott E, Hong David S, Gibbons Don L, Olson Peter, Christensen James G, Heymach John V
细胞生物学
肺癌
肿瘤免疫
发表日期：2025
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Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer

阿达格拉西布联合西妥昔单抗治疗KRASG12C突变转移性结直肠癌患者的疗效和安全性

期刊:Cancer Discovery
影响因子:33.3
doi:10.1158/2159-8290.CD-24-0217
Yaeger, Rona; Uboha, Nataliya V; Pelster, Meredith S; Bekaii-Saab, Tanios S; Barve, Minal; Saltzman, Joel; Sabari, Joshua K; Peguero, Julio A; Paulson, Andrew Scott; Jänne, Pasi A; Cruz-Correa, Marcia; Anderes, Kenna; Velastegui, Karen; Yan, Xiaohong; Der-Torossian, Hirak; Klempner, Samuel J; Kopetz, Scott E
RAS
肿瘤
肠癌
肿瘤免疫
发表日期：2024
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A path to translation: How 3D patient tumor avatars enable next generation precision oncology

通往转化之路：3D患者肿瘤虚拟化身如何助力下一代精准肿瘤学

期刊:Cancer Cell
影响因子:44.5
doi:10.1016/j.ccell.2022.09.017
Bose, Shree; Barroso, Margarida; Chheda, Milan G; Clevers, Hans; Elez, Elena; Kaochar, Salma; Kopetz, Scott E; Li, Xiao-Nan; Meric-Bernstam, Funda; Meyer, Clifford A; Mou, Haiwei; Naegle, Kristen M; Pera, Martin F; Perova, Zinaida; Politi, Katerina A; Raphael, Benjamin J; Robson, Paul; Sears, Rosalie C; Tabernero, Josep; Tuveson, David A; Welm, Alana L; Welm, Bryan E; Willey, Christopher D; Salnikow, Konstantin; Chuang, Jeffrey H; Shen, Xiling
3D/类器官
肿瘤
肿瘤免疫
发表日期：2022
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BCL-X(L) PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRAS(G12C)-mutated cancers

BCL-X(L) PROTAC降解剂DT2216与sotorasib在KRAS(G12C)突变癌症的临床前模型中具有协同作用

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-022-01241-3
Khan, Sajid; Wiegand, Janet; Zhang, Peiyi; Hu, Wanyi; Thummuri, Dinesh; Budamagunta, Vivekananda; Hua, Nan; Jin, Lingtao; Allegra, Carmen J; Kopetz, Scott E; Zajac-Kaye, Maria; Kaye, Frederic J; Zheng, Guangrong; Zhou, Daohong
RAS
肿瘤
肿瘤免疫
发表日期：2022
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Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer

染色质状态动态变化为结直肠癌增强子亚型的特定治疗策略提供了依据

期刊:Gut
影响因子:25.8
doi:10.1136/gutjnl-2020-322835
Orouji, Elias; Raman, Ayush T; Singh, Anand K; Sorokin, Alexey; Arslan, Emre; Ghosh, Archit K; Schulz, Jonathan; Terranova, Christopher; Jiang, Shan; Tang, Ming; Maitituoheti, Mayinuer; Callahan, Scot C; Barrodia, Praveen; Tomczak, Katarzyna; Jiang, Yingda; Jiang, Zhiqin; Davis, Jennifer S; Ghosh, Sukhen; Lee, Hey Min; Reyes-Uribe, Laura; Chang, Kyle; Liu, Yusha; Chen, Huiqin; Azhdarinia, Ali; Morris, Jeffrey; Vilar, Eduardo; Carmon, Kendra S; Kopetz, Scott E; Rai, Kunal
肿瘤
肠癌
肿瘤免疫
发表日期：2022
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Preliminary Analysis of Liquid Biopsy after Hepatectomy for Colorectal Liver Metastases

结直肠癌肝转移肝切除术后液体活检的初步分析

期刊:Journal of the American College of Surgeons
影响因子:3.4
doi:10.1016/j.jamcollsurg.2021.02.011
Mason, Meredith C; Tzeng, Ching-Wei D; Tran Cao, Hop S; Aloia, Thomas A; Newhook, Timothy E; Overman, Michael J; Kopetz, Scott E; Vauthey, Jean-Nicolas; Chun, Yun Shin
肿瘤
肠癌
肿瘤免疫
发表日期：2021
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Deleterious Effect of RAS and Evolutionary High-risk TP53 Double Mutation in Colorectal Liver Metastases

RAS 和进化高危 TP53 双突变对结直肠癌肝转移的有害影响

期刊:Annals of Surgery
影响因子:6.4
doi:10.1097/SLA.0000000000002450
Chun, Yun Shin; Passot, Guillaume; Yamashita, Suguru; Nusrat, Maliha; Katsonis, Panagiotis; Loree, Jonathan M; Conrad, Claudius; Tzeng, Ching-Wei D; Xiao, Lianchun; Aloia, Thomas A; Eng, Cathy; Kopetz, Scott E; Lichtarge, Olivier; Vauthey, Jean-Nicolas
肿瘤
肠癌
肿瘤免疫
P53
RAS
发表日期：2019
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Embryonic Origin of Primary Colon Cancer Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colon Cancer Liver Metastases

原发性结肠癌的胚胎起源可预测接受结肠癌肝转移切除术患者的病理反应和生存率

期刊:Annals of Surgery
影响因子:6.4
doi:10.1097/SLA.0000000000002087
Yamashita, Suguru; Brudvik, Kristoffer Watten; Kopetz, Scott E; Maru, Dipen; Clarke, Callisia N; Passot, Guillaume; Conrad, Claudius; Chun, Yun Shin; Aloia, Thomas A; Vauthey, Jean-Nicolas
肿瘤
肠癌
肿瘤免疫
发表日期：2018
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Impact of Prior Hepatectomy History on Local Tumor Progression after Percutaneous Ablation of Colorectal Liver Metastases

既往肝切除史对经皮消融结直肠癌肝转移瘤后局部肿瘤进展的影响

期刊:Journal of Vascular and Interventional Radiology
影响因子:2.6
doi:10.1016/j.jvir.2017.10.026
Odisio, Bruno C; Yamashita, Suguru; Huang, Steven Y; Kopetz, Scott E; Ahrar, Kamran; Mizuno, Takashi; Conrad, Claudius; Aloia, Thomas A; Chun, Yun Shin; Gupta, Sanjay; Vauthey, Jean-Nicolas
肿瘤
肠癌
肿瘤免疫
发表日期：2018
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