日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Acidosis-induced p38-kinase activation triggers an IL-6-mediated crosstalk of renal proximal tubule cells with fibroblasts leading to their inflammatory response.

酸中毒诱导的 p38 激酶激活触发 IL-6 介导的肾近端小管细胞与成纤维细胞的串扰,从而导致其炎症反应

Schulz Marie-Christin, Wolff Nathalie, Kopf Michael, Gekle Micheal

Early-phase impact of obesity-associated stress on murine vascular smooth muscle cells depends on EGFR and sex

肥胖相关应激对小鼠血管平滑肌细胞的早期影响取决于EGFR和性别

Dubourg, Virginie; Rabe, Sindy; Nasiri-Ansari, Narjes; Kopf, Michael; Mildenberger, Sigrid; Schwerdt, Gerald; Schreier, Barbara; Gekle, Michael

Physiological regulation of oral saliva ion composition and flow rate are not coupled in healthy humans-Partial revision of our current knowledge required

健康人口腔唾液离子组成和流速的生理调节并非相互关联——需要对我们目前的认知进行部分修正。

Schwerdt, Gerald; Schulz, Marie-Christin; Kopf, Michael; Mildenberger, Sigrid; Reime, Sarah; Gekle, Michael

Crosstalk with renal proximal tubule cells drives acidosis-induced inflammatory response and dedifferentiation of fibroblasts via p38-singaling

与肾近端小管细胞的相互作用通过p38信号通路驱动酸中毒诱导的炎症反应和成纤维细胞去分化

Schulz, Marie-Christin; Kopf, Michael; Gekle, Michael

EGFR activation differentially affects the inflammatory profiles of female human aortic and coronary artery endothelial cells

EGFR激活对女性人主动脉和冠状动脉内皮细胞的炎症特征产生不同的影响

Dubourg, Virginie; Schwerdt, Gerald; Schreier, Barbara; Kopf, Michael; Mildenberger, Sigrid; Benndorf, Ralf A; Gekle, Michael

The nephrotoxin ochratoxin a impairs resilience of energy homeostasis of human proximal tubule cells

肾毒素赭曲霉毒素A会损害人近端肾小管细胞能量稳态的恢复能力。

Schwerdt, Gerald; Kopf, Michael; Gekle, Michael

Hypothesis-generating analysis of the impact of non-damaging metabolic acidosis on the transcriptome of different cell types: Integrated stress response (ISR) modulation as general transcriptomic reaction to non-respiratory acidic stress?

对非损伤性代谢性酸中毒对不同细胞类型转录组的影响进行假设生成分析:整合应激反应 (ISR) 调节作为对非呼吸性酸应激的一般转录组反应?

Dubourg, Virginie; Schulz, Marie-Christin; Terpe, Philipp; Ruhs, Stefanie; Kopf, Michael; Gekle, Michael

The mineralocorticoid receptor leads to increased expression of EGFR and T-type calcium channels that support HL-1 cell hypertrophy

盐皮质激素受体导致 EGFR 和 T 型钙通道表达增加,从而支持 HL-1 细胞肥大

Katharina Stroedecke #, Sandra Meinel #, Fritz Markwardt, Udo Kloeckner, Nicole Straetz, Katja Quarch, Barbara Schreier, Michael Kopf, Michael Gekle, Claudia Grossmann

Weighted Correlation Network Analysis Reveals CDK2 as a Regulator of a Ubiquitous Environmental Toxin-Induced Cell-Cycle Arrest

加权相关网络分析揭示 CDK2 是普遍存在的环境毒素诱导的细胞周期阻滞的调节因子

Virginie Dubourg ,Alexander Nolze ,Michael Kopf ,Michael Gekle ,Gerald Schwerdt

Monitoring gradient formation in a jet aerated bioreactor

监测喷射曝气生物反应器中的梯度形成

Weber, Sebastian; Schaepe, Sebastian; Freyer, Stephan; Kopf, Michael-Helmut; Dietzsch, Christian