日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PAR2, in preclinical models of migraine.

MEDI0618 是一种 pH 依赖性单克隆抗体，靶向 PAR2，在偏头痛的临床前模型中疗效

期刊:Brain
影响因子:11.7
doi:10.1093/brain/awae344
Kopruszinski Caroline M, Linley John E, Thornton Peter, Walker Alison S, Newton Philip, Podichetty Sadhana, Ruparel Radhey Hemendra, Moreira de Souza Luiz Henrique, Navratilova Edita, Meno-Tetang Guy, Gurrell Ian, Dodick David W, Dobson Claire, Chessell Tharani, Porreca Frank, Chessell Iain
免疫/内分泌
发表日期：2025
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A prolactin-targeting antibody to prevent stress-induced peripheral nociceptor sensitization and female postoperative pain

一种靶向催乳素的抗体，用于预防应激诱导的外周伤害感受器敏化和女性术后疼痛

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2501229122
Stratton, Harrison J; Dolatyari, Mahdi; Kopruszinski, Carol; Ghetti, Andre; Maciuba, Stephanie; Bowden, Greg; Rivière, Pierre; Barber, Kara; Dodick, David W; Edorh, Edel; Dumaire, Nicolas; Moutal, Aubin; Navratilova, Edita; Porreca, Frank
发表日期：2025
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OnabotulinumtoxinA inhibits dysregulation of descending pain modulation following mild traumatic brain injury in mice

A型肉毒杆菌毒素可抑制小鼠轻度创伤性脑损伤后下行疼痛调节的失调

期刊:Journal of Headache and Pain
影响因子:7.9
doi:10.1186/s10194-025-02159-0
Vizin, Robson C Lillo; Kopruszinski, Caroline M; Oyarzo, Janice N; Dodick, David W; Broide, Ron S; Brideau-Andersen, Amy D; Brin, Mitchell F; Anderson, Trent; Navratilova, Edita; Porreca, Frank
神经科学
发表日期：2025
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Descending facilitation from rostral ventromedial medulla mu opioid receptor-expressing neurons is necessary for maintenance of sensory and affective dimensions of chronic neuropathic pain

来自延髓腹内侧部表达μ阿片受体的神经元的下行易化作用对于维持慢性神经性疼痛的感觉和情感维度是必要的。

期刊:Pain
影响因子:5.5
doi:10.1097/j.pain.0000000000003360
Dogrul, Bekir Nihat; Machado Kopruszinski, Caroline; Dolatyari Eslami, Mahdi; Watanabe, Moe; Luo, Shizhen; Moreira de Souza, Luiz Henrique; Vizin, Robson Lilo; Yue, Xu; Palmiter, Richard D; Navratilova, Edita; Porreca, Frank
信号转导
神经科学
发表日期：2025
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Chronification of migraine sensitizes to CGRP in male and female mice.

偏头痛的慢性化会使雄性和雌性小鼠对 CGRP 更加敏感

期刊:Cephalalgia
影响因子:4.6
doi:10.1177/03331024251317446
Guzman Gege, Kopruszinski Caroline M, Barber Kara R, Lillo Vizin Robson C, Dodick David W, Navratilova Edita, Porreca Frank
神经科学
CGRP
偏头痛
发表日期：2025
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Female-selective mechanisms promoting migraine

女性选择性机制促进偏头痛

期刊:Journal of Headache and Pain
影响因子:7.9
doi:10.1186/s10194-024-01771-w
Singh, Shagun; Kopruszinski, Caroline M; Watanabe, Moe; Dodick, David W; Navratilova, Edita; Porreca, Frank
偏头痛
神经科学
发表日期：2024
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Cortical kappa opioid receptors integrate negative affect and sleep disturbance

皮质 κ 阿片受体整合负面影响和睡眠障碍

期刊:Translational Psychiatry
影响因子:5.8
doi:10.1038/s41398-024-03123-3
Robson C Lillo Vizin, Hisakatsu Ito, Caroline M Kopruszinski, Megumi Ikegami, Daigo Ikegami, Xu Yue, Edita Navratilova, Aubin Moutal, Stephen L Cowen, Frank Porreca
信号转导
发表日期：2024
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A male-specific mechanism of meningeal nociceptor sensitization promoting migraine headache.

男性特有的脑膜伤害感受器敏化机制促进偏头痛的发生

期刊:Cephalalgia
影响因子:4.6
doi:10.1177/03331024241281493
Kopruszinski Caroline M, Lee Grace, Martin Laurent K, Barber Kara R, Moutal Aubin, Dodick David W, Navratilova Edita, Porreca Frank
其它
发表日期：2024
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Unraveling the directional relationship of sleep and migraine-like pain

揭示睡眠与偏头痛样疼痛的方向关系

期刊:Brain Communications
影响因子:4.1
doi:10.1093/braincomms/fcae051
Robson C Lillo Vizin, Caroline M Kopruszinski, Paula M Redman, Hisakatsu Ito, Jill Rau, David W Dodick, Edita Navratilova, Frank Porreca
信号转导
发表日期：2024
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Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance

慢性疼痛会激活下丘脑强啡肽/κ阿片受体信号通路，从而促进觉醒和警觉。

期刊:Brain
影响因子:11.7
doi:10.1093/brain/awac153
Ito, Hisakatsu; Navratilova, Edita; Vagnerova, Barbora; Watanabe, Moe; Kopruszinski, Carol; Moreira de Souza, Luiz H; Yue, Xu; Ikegami, Daigo; Moutal, Aubin; Patwardhan, Amol; Khanna, Rajesh; Yamazaki, Mitsuaki; Guerrero, Miguel; Rosen, Hugh; Roberts, Ed; Neugebauer, Volker; Dodick, David W; Porreca, Frank
信号转导
神经科学
免疫/内分泌
发表日期：2023
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