Early initiation of hydroxyurea (hydroxycarbamide) using individualised, pharmacokinetics-guided dosing can produce sustained and nearly pancellular expression of fetal haemoglobin in children with sickle cell anaemia
在镰状细胞贫血症患儿中，早期采用个体化的、药代动力学指导的羟基脲（羟基脲）给药方案，可使胎儿血红蛋白持续且几乎在全细胞范围内表达。
期刊:British Journal of Haematology
影响因子:3.8
doi:10.1111/bjh.17663
Quinn, Charles T; Niss, Omar; Dong, Min; Pfeiffer, Amanda; Korpik, Jennifer; Reynaud, Mary; Bonar, Holly; Kalfa, Theodosia A; Smart, Luke R; Malik, Punam; Ware, Russell E; Vinks, Alexander A; McGann, Patrick T
