日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Exposure-Response Relationships for Axatilimab in Patients with Chronic Graft-Versus-Host Disease

阿沙替利单抗治疗慢性移植物抗宿主病患者的暴露-反应关系

Yang, Yan-Ou; Volkova, Alina; Sokolov, Victor; Liu, Xing; Leon, Cristina; Kosinsky, Yuri; Sheng, Jennifer; Chen, Xuejun

Semimechanistic Population PK/PD Modeling of Axatilimab in Healthy Participants and Patients With Solid Tumors or Chronic Graft-Versus-Host Disease.

对健康受试者和实体瘤或慢性移植物抗宿主病患者进行阿沙替利单抗的半机制群体药代动力学/药效动力学建模

Yang Yan-Ou, Sokolov Victor, Volkova Alina, Liu Xing, Leon Cristina, Kosinsky Yuri, Barker Breann, Zhang Xuecheng, Ordentlich Peter, Sheng Jennifer, Chen Xuejun

Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19

卡莫司他甲磺酸盐半机制药代动力学-药效学模型预测其对COVID-19中SARS-CoV-2的疗效

Kosinsky, Yuri; Peskov, Kirill; Stanski, Donald R; Wetmore, Diana; Vinetz, Joseph

Quantitative Mechanistic Modeling in Support of Pharmacological Therapeutics Development in Immuno-Oncology

定量机制建模在免疫肿瘤学药物治疗开发中的应用

Peskov, Kirill; Azarov, Ivan; Chu, Lulu; Voronova, Veronika; Kosinsky, Yuri; Helmlinger, Gabriel

Quantitative Systems Pharmacology: An Exemplar Model-Building Workflow With Applications in Cardiovascular, Metabolic, and Oncology Drug Development

定量系统药理学:一个示例性的模型构建工作流程及其在心血管、代谢和肿瘤药物研发中的应用

Helmlinger, Gabriel; Sokolov, Victor; Peskov, Kirill; Hallow, Karen M; Kosinsky, Yuri; Voronova, Veronika; Chu, Lulu; Yakovleva, Tatiana; Azarov, Ivan; Kaschek, Daniel; Dolgun, Artem; Schmidt, Henning; Boulton, David W; Penland, Robert C

Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems model

放射治疗与PD-(L)1联合治疗:基于预测系统模型的免疫反应和剂量优化

Kosinsky, Yuri; Dovedi, Simon J; Peskov, Kirill; Voronova, Veronika; Chu, Lulu; Tomkinson, Helen; Al-Huniti, Nidal; Stanski, Donald R; Helmlinger, Gabriel

SA6. How Reliable are Peripheral Biomarkers of Inflammation in Schizophrenia?

SA6. 精神分裂症患者外周炎症生物标志物的可靠性如何?

Shulgin, Boris; Helmlinger, Gabriel; Kosinsky, Yuri; Burgess, Martin; Boerrigter, Danny; Weickert, Thomas; Lenroot, Rhoshel; O’Donnell, Maryanne; Galletly, Cherrie; Liu, Dennis; Cadiz, Roxanne; Jacomb, Isabella; Catts, Vibeke Sørensen; Weickert, Cyndi Shannon

Molecular modelling of the nucleotide-binding domain of Wilson's disease protein: location of the ATP-binding site, domain dynamics and potential effects of the major disease mutations

威尔逊病蛋白核苷酸结合域的分子建模:ATP结合位点的定位、结构域动力学以及主要致病突变的潜在影响

Efremov, Roman G; Kosinsky, Yuri A; Nolde, Dmitry E; Tsivkovskii, Ruslan; Arseniev, Alexander S; Lutsenko, Svetlana