日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inhibition of FGFR signaling with infigratinib improves linear bone growth in the female Aga2/+ mouse model of osteogenesis imperfecta

使用infigratinib抑制FGFR信号传导可改善成骨不全症雌性Aga2/+小鼠模型的线性骨骼生长

期刊:JBMR Plus
影响因子:2.4
doi:10.1093/jbmrpl/ziag005
Kot, Alexander; Wight, Caroline; Bagheri, Roya; Wachtell, Davis; Rios, Alma; Bober, Benjamin; Chun, Cora; Krejci, Pavel; Zieba, Jennifer; Krakow, Deborah
信号转导
发表日期：2026
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Endoplasmic reticulum stress disrupts signaling via altered processing of transmembrane receptors

内质网应激通过改变跨膜受体的加工过程来破坏信号传导。

期刊:Cell Communication and Signaling
影响因子:8.9
doi:10.1186/s12964-025-02208-w
Bosakova, Michaela; Abraham, Sara P; Wachtell, Davis; Zieba, Jennifer T; Kot, Alexander; Nita, Alexandru; Czyrek, Aleksandra Anna; Koudelka, Adolf; Ursachi, Vlad-Constantin; Feketova, Zuzana; Rico-Llanos, Gustavo; Svozilova, Katerina; Kocerova, Petra; Fafilek, Bohumil; Gregor, Tomas; Kotaskova, Jana; Duran, Ivan; Vanhara, Petr; Doubek, Michael; Mayer, Jiri; Soucek, Karel; Krakow, Deborah; Krejci, Pavel
信号转导
内质网应激
发表日期：2025
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Loss of the long form of Plod2 phenocopies contractures of Bruck syndrome-osteogenesis imperfecta.

Plod2 长型基因的缺失会模拟布鲁克综合征-成骨不全症的挛缩症状

期刊:Journal of Bone and Mineral Research
影响因子:5.9
doi:10.1093/jbmr/zjae124
Kot Alexander, Chun Cora, Martin Jorge H, Wachtell Davis, Hudson David, Weis MaryAnn, Marks Haley, Srivastava Siddharth, Eyre David R, Duran Ivan, Zieba Jennifer, Krakow Deborah
骨科研究
发表日期：2024
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Altered Sox9 and FGF signaling gene expression in Aga2 OI mice negatively affects linear growth

Aga2 OI小鼠中Sox9和FGF信号通路基因表达的改变对线性生长产生负面影响

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.171984
Zieba, Jennifer; Nevarez, Lisette; Wachtell, Davis; Martin, Jorge H; Kot, Alexander; Wong, Sereen; Cohn, Daniel H; Krakow, Deborah
信号转导
发表日期：2023
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Selective inhibition of progesterone receptor in osteochondral progenitor cells, but not in mature chondrocytes, modulated subchondral bone structures

选择性抑制骨软骨祖细胞（而非成熟软骨细胞）中的孕激素受体，可调节软骨下骨结构。

期刊:
影响因子:
doi:10.1016/j.bone.2019.115196
Dai, Chenlin; Jia, Junjing; Kot, Alexander; Liu, Xueping; Liu, Lixian; Jiang, Min; Lane, Nancy E; Wise, Barton L; Yao, Wei
信号转导
细胞生物学
免疫/内分泌
发表日期：2020
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Sex-Dependent, Osteoblast Stage-Specific Effects of Progesterone Receptor on Bone Acquisition

孕激素受体对骨骼形成具有性别依赖性和成骨细胞阶段特异性的影响

期刊:Journal of Bone and Mineral Research
影响因子:5.9
doi:10.1002/jbmr.3186
Zhong, Zhendong A; Kot, Alexander; Lay, Yu-An E; Zhang, Hongliang; Jia, Junjing; Lane, Nancy E; Yao, Wei
信号转导
细胞生物学
免疫/内分泌
发表日期：2017
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A Novel Hybrid Compound LLP2A-Ale Both Prevented and Rescued the Osteoporotic Phenotype in a Mouse Model of Glucocorticoid-Induced Osteoporosis

一种新型杂合化合物LLP2A-Ale既能预防又能挽救糖皮质激素诱导的小鼠骨质疏松症模型中的骨质疏松表型

期刊:Calcified Tissue International
影响因子:3.2
doi:10.1007/s00223-016-0195-6
Mohan, Geetha; Lay, Evan Yu-An; Berka, Haley; Ringwood, Lorna; Kot, Alexander; Chen, Haiyan; Yao, Wei; Lane, Nancy E
代谢
Mouse
免疫/内分泌
骨质疏松
发表日期：2017
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Improved Mobilization of Exogenous Mesenchymal Stem Cells to Bone for Fracture Healing and Sex Difference

提高外源间充质干细胞向骨骼的动员能力以促进骨折愈合及性别差异

期刊:Stem Cells
影响因子:3.6
doi:10.1002/stem.2433
Yao, Wei; Lay, Yu-An Evan; Kot, Alexander; Liu, Ruiwu; Zhang, Hongliang; Chen, Haiyan; Lam, Kit; Lane, Nancy E
细胞生物学
发育与干细胞
骨折
干细胞
发表日期：2016
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β-Ecdysone Augments Peak Bone Mass in Mice of Both Sexes

β-蜕皮激素可增加雌雄小鼠的峰值骨量

期刊:Clinical Orthopaedics and Related Research
影响因子:4.4
doi:10.1007/s11999-015-4246-5
Dai, Weiwei; Zhang, HongLiang; Zhong, Zhendong A; Jiang, Li; Chen, Haiyan; Lay, Yu-An Evan; Kot, Alexander; Ritchie, Robert O; Lane, Nancy E; Yao, Wei
免疫/内分泌
发表日期：2015
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Prevention of glucocorticoid induced bone changes with beta-ecdysone

β-蜕皮激素预防糖皮质激素引起的骨骼变化

期刊:
影响因子:
doi:10.1016/j.bone.2015.01.001
Dai, Weiwei; Jiang, Li; Lay, Yu-An Evan; Chen, Haiyan; Jin, Guoqin; Zhang, Hongliang; Kot, Alexander; Ritchie, Robert O; Lane, Nancy E; Yao, Wei
免疫/内分泌
发表日期：2015
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