日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.

配体与远端位点的结合,从热力学角度纠正了人类囊性纤维化跨膜传导调节因子中的 F508del 突变

Wang Chi, Aleksandrov Andrei A, Yang Zhengrong, Forouhar Farhad, Proctor Elizabeth A, Kota Pradeep, An Jianli, Kaplan Anna, Khazanov Netaly, Boël Grégory, Stockwell Brent R, Senderowitz Hanoch, Dokholyan Nikolay V, Riordan John R, Brouillette Christie G, Hunt John F

Gain-of-Function Mutation W493R in the Epithelial Sodium Channel Allosterically Reconfigures Intersubunit Coupling

上皮钠通道功能获得性突变W493R通过变构方式重构亚基间偶联

Shobair, Mahmoud; Dagliyan, Onur; Kota, Pradeep; Dang, Yan L; He, Hong; Stutts, M Jackson; Dokholyan, Nikolay V

Computational approaches to understanding protein aggregation in neurodegeneration

利用计算方法理解神经退行性疾病中的蛋白质聚集

Redler, Rachel L; Shirvanyants, David; Dagliyan, Onur; Ding, Feng; Kim, Doo Nam; Kota, Pradeep; Proctor, Elizabeth A; Ramachandran, Srinivas; Tandon, Arpit; Dokholyan, Nikolay V

Intra- and inter-subunit disulfide bond formation is nonessential in adeno-associated viral capsids

腺相关病毒衣壳中亚基内和亚基间二硫键的形成并非必需。

Pulicherla, Nagesh; Kota, Pradeep; Dokholyan, Nikolay V; Asokan, Aravind

Approaches for probing the sequence space of substrates recognized by molecular chaperones

探测分子伴侣识别底物序列空间的方法

Kota, Pradeep; Dokholyan, Nikolay V

Automated minimization of steric clashes in protein structures

蛋白质结构中空间位阻冲突的自动最小化

Ramachandran, Srinivas; Kota, Pradeep; Ding, Feng; Dokholyan, Nikolay V

Gaia: automated quality assessment of protein structure models

Gaia:蛋白质结构模型的自动化质量评估

Kota, Pradeep; Ding, Feng; Ramachandran, Srinivas; Dokholyan, Nikolay V

Engineered allosteric activation of kinases in living cells

活细胞中激酶的工程化变构激活

Karginov, Andrei V; Ding, Feng; Kota, Pradeep; Dokholyan, Nikolay V; Hahn, Klaus M

Identification of a consensus motif in substrates bound by a Type I Hsp40

鉴定I型Hsp40结合底物中的共有基序

Kota, Pradeep; Summers, Daniel W; Ren, Hong-Yu; Cyr, Douglas M; Dokholyan, Nikolay V