日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deeper neuronal and glial proteomic insights using an optimized pipeline for proximity labeling proteomics

利用优化的邻近标记蛋白质组学流程,获得更深入的神经元和胶质细胞蛋白质组学信息

Jang, Wooyoung Eric; Srivastava, Upasna; Brandelli, Amanda D; Kumar, Prateek; Espinosa-Garcia, Claudia; Kour, Dilpreet; Kumari, Rashmi; Rangaraju, Srikant

Pathogenic tau in the mouse locus coeruleus produces noradrenergic hyperactivity and neuropsychiatric phenotypes reminiscent of early Alzheimer's disease

小鼠蓝斑核中的致病性tau蛋白会导致去甲肾上腺素能过度活跃和类似于早期阿尔茨海默病的神经精神表型。

Korukonda, Anu; Blankenship, Harris E; Kam, Korey; Kour, Dilpreet; Espinosa-Garcia, Claudia; Jang, Wooyoung Eric; Srivastava, Upasna; Mulvey, Bernard; Tish, Margaret M; Witztum, Ronit; Ramelow, Christina C; Pate, Brittany S; Liles, L Cameron; Lu, Linyue; Atallah, Jake; Guo, Eugene; Martinowich, Keri; Sharpe, Amanda L; Varga, Andrew W; Rangaraju, Srikant; Beckstead, Michael J; Weinshenker, David

Neuroinflammatory stress preferentially impacts synaptic MAPK signaling and mitochondria in excitatory neurons.

神经炎症应激优先影响兴奋性神经元中的突触 MAPK 信号传导和线粒体。

Espinosa-Garcia Claudia, Srivastava Upasna, Kumar Prateek, Kour Dilpreet, Malepati Sneha, Tobin Brendan R, Xiao Hailian, Sunna Sydney, Bowen Christine A, Cheng Lihong, Bagchi Pritha, Duong Duc M, Whitworth Ted J, Liu Xinran, Seyfried Nicholas T, Wood Levi B, Faundez Victor, Rangaraju Srikant

Identification of Novel Kv1.3 Channel-Interacting Proteins Using Proximity Labelling in T-Cells.

利用邻近标记法在 T 细胞中鉴定新型 Kv1.3 通道相互作用蛋白。

Kour Dilpreet, Bowen Christine A, Srivastava Upasna, Nguyen Hai M, Kumari Rashmi, Kumar Prateek, Brandelli Amanda D, Bitarafan Sara, Tobin Brendan R, Wood Levi B, Seyfried Nicholas T, Wulff Heike, Rangaraju Srikant

MRI measures of neuropathology in neurodegenerative disease

神经退行性疾病中神经病理学的MRI测量

Kumari, Rashmi; Bowen, Christine; Srivastava, Upasna; Brandelli, Amanda Dabdab; Kumar, Prateek; Kour, Dilpreet; Malepati, Sneha; Jang, Wooyoung Eric; Bromwich, Mark; Zeng, Hollis; Sing, Anson; Sloan, Steven A; Wulff, Heike; Rangaraju, Srikant; Jonkman, Laura E; Reijner, Niels; Bouwman, Maud MA; Wesseling, Alex J; Deshayes, Natasja A C; Lin, Chen‐Pei; Frigerio, Irene; Pijnenburg, Yolande AL; van der Weerd, Louise; Barkhof, Frederik; Rozemuller, Annemieke JM; de Berg, Wilma DJ Van; Jonkman, Laura E; Reijner, Niels; Bouwman, Maud MA; Wesseling, Alex J; Deshayes, Natasja A C; Lin, Chen‐Pei; Frigerio, Irene; Pijnenburg, Yolande AL; van der Weerd, Louise; Barkhof, Frederik; Rozemuller, Annemieke JM; de Berg, Wilma DJ Van

Neuroinflammatory Stress Preferentially Impacts Synaptic MAPK Signaling and Mitochondria in Excitatory Neurons

神经炎症应激优先影响兴奋性神经元中的突触MAPK信号通路和线粒体

Espinosa-Garcia, Claudia; Srivastava, Upasna; Kumar, Prateek; Kour, Dilpreet; Malepati, Sneha; Tobin, Brendan R; Xiao, Hailian; Sunna, Sydney; Bowen, Christine A; Cheng, Lihong; Bagchi, Pritha; Duong, Duc M; Whitworth, Ted J; Xinran, Liu; Seyfried, Nicholas T; Wood, Levi B; Faundez, Victor; Rangaraju, Srikant

Bisdemethoxycurcumin mitigates Alzheimer disease pathology through autophagy-mediated reduction of senescence and amyloid beta.

双去甲氧基姜黄素通过自噬介导的减少衰老和β-淀粉样蛋白来减轻阿尔茨海默病病理

Khajuria Parul, Kour Dilpreet, Sharma Kuhu, Singh Lakhvinder, Banoo Razia, Manhas Diksha, Ramajayan P, Nandi Utpal, Bharate Sandip, Ahmed Zabeer, Kumar Ajay

ADME/PK Insights of Crocetin: A Molecule Having an Unusual Chemical Structure with Druglike Features

藏红花酸的 ADME/PK 见解:一种具有不寻常化学结构和类药物特征的分子

Diksha Manhas, Sumit Dhiman, Harpreet Kour, Dilpreet Kour, Kuhu Sharma, Priya Wazir, Bhavna Vij, Ajay Kumar, Sanghapal D Sawant, Zabeer Ahmed, Utpal Nandi

Gentiacaulein inhibits glucose transport to induce PRKAA1-mediated autophagy to clear amyloid beta and associated inflammation in primary astrocytes.

龙胆碱抑制葡萄糖转运,诱导 PRKAA1 介导的自噬,从而清除原代星形胶质细胞中的淀粉样蛋白β和相关炎症

Sharma Ankita, Kaur Sukhleen, Wani Abubakar, Kour Dilpreet, Ali Mehboob, Ali Syed Mudassir, Singh Lakhvinder, Gour Abhishek, Nandi Utpal, Datt Manish, Sharma Parduman Raj, Weihl Conrad C, Singh Gurdarshan, Kumar Ajay

Glabridin Plays Dual Action to Augment the Efficacy and Attenuate the Hepatotoxicity of Methotrexate in Arthritic Rats

甘草定具有双重作用,可增强甲氨蝶呤对关节炎大鼠的疗效并减轻其肝毒性。

Dogra, Ashish; Kour, Dilpreet; Bhardwaj, Mahir; Dhiman, Sumit; Kumar, Amit; Vij, Bhavna; Kumar, Ajay; Nandi, Utpal