日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficient multi-kilobase knock-ins in mice and cell lines using CRISPR/Cas9 and rAAV donors with unbiased whole-genome characterization by LOCK-seq

利用 CRISPR/Cas9 和 rAAV 供体,在小鼠和细胞系中高效实现多千碱基基因敲入,并通过 LOCK-seq 进行无偏倚的全基因组表征。

Sentmanat, Monica F; Wang, Zi Teng; Kouranova, Evguenia; Peters, Samuel T; Chan, Wan Ching; Lin, Jed; Miao, Yong; White, J Michael; Wallace, Mia; Cui, Xiaoxia

Adipose Tissue Overexpression of Nicotinamide Phosphoribosyltransferase Prevents Metabolic Dysfunction in Obese Mice

脂肪组织中烟酰胺磷酸核糖转移酶的过表达可预防肥胖小鼠的代谢功能障碍

Ferguson, Daniel; Gadson, Elise I; Markan, Kathleen R; Yoshino, Jun; Lin, Maxwell; Habibi, Mohammad; Tiash, Snigdha; Cui, Xiaoxia; Kouranova, Evguenia; Franczak, Edziu; Guo, Qiuyuan; Kealing, Jill; Pietka, Terri A; Liss, Kim H H; Thyfault, John P; Patti, Gary J; Finck, Brian N; Crewe, Clair; Mukherjee, Sandip

Bi-allelic CAMSAP1 variants cause a clinically recognizable neuronal migration disorder

CAMSAP1双等位基因变异会导致临床上可识别的神经元迁移障碍。

Khalaf-Nazzal, Reham; Fasham, James; Inskeep, Katherine A; Blizzard, Lauren E; Leslie, Joseph S; Wakeling, Matthew N; Ubeyratna, Nishanka; Mitani, Tadahiro; Griffith, Jennifer L; Baker, Wisam; Al-Hijawi, Fida'; Keough, Karen C; Gezdirici, Alper; Pena, Loren; Spaeth, Christine G; Turnpenny, Peter D; Walsh, Joseph R; Ray, Randall; Neilson, Amber; Kouranova, Evguenia; Cui, Xiaoxia; Curiel, David T; Pehlivan, Davut; Akdemir, Zeynep Coban; Posey, Jennifer E; Lupski, James R; Dobyns, William B; Stottmann, Rolf W; Crosby, Andrew H; Baple, Emma L

Highly reliable creation of floxed alleles by electroporating single-cell embryos

利用电穿孔法在单细胞胚胎中高效构建floxed等位基因

Sentmanat, Monica F; White, J Michael; Kouranova, Evguenia; Cui, Xiaoxia

CRISPRs for Optimal Targeting: Delivery of CRISPR Components as DNA, RNA, and Protein into Cultured Cells and Single-Cell Embryos

CRISPR技术实现最佳靶向:将CRISPR组分以DNA、RNA和蛋白质的形式递送至培养细胞和单细胞胚胎

Kouranova, Evguenia; Forbes, Kevin; Zhao, Guojun; Warren, Joe; Bartels, Angela; Wu, Yumei; Cui, Xiaoxia

CRISPR/Cas9-Mediated Insertion of loxP Sites in the Mouse Dock7 Gene Provides an Effective Alternative to Use of Targeted Embryonic Stem Cells

CRISPR/Cas9 介导的小鼠 Dock7 基因中 loxP 位点的插入为使用靶向胚胎干细胞提供了一种有效的替代方案

Kathleen A Bishop, Anne Harrington, Evguenia Kouranova, Edward J Weinstein, Clifford J Rosen, Xiaoxia Cui, Lucy Liaw

Regulation of dopamine presynaptic markers and receptors in the striatum of DJ-1 and Pink1 knockout rats

DJ-1 和 Pink1 基因敲除大鼠纹状体中多巴胺突触前标志物和受体的调节

Jianjun Sun, Evguenia Kouranova, Xiaoxia Cui, Robert H Mach, Jinbin Xu

An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition

针对磷酸化 tau 蛋白的超特异性禽抗体揭示了磷酸表位识别的独特机制

Heather H Shih, Chao Tu, Wei Cao, Anne Klein, Renee Ramsey, Brian J Fennell, Matthew Lambert, Deirdre Ní Shúilleabháin, Bénédicte Autin, Eugenia Kouranova, Sri Laxmanan, Steven Braithwaite, Leeying Wu, Mostafa Ait-Zahra, Anthony J Milici, Jo Ann Dumin, Edward R LaVallie, Maya Arai, Christopher Corco

The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimer's disease

LXR 激动剂 TO901317 选择性降低海马 Abeta42 并改善阿尔茨海默病 Tg2576 小鼠模型的记忆力

David R Riddell, Hua Zhou, Thomas A Comery, Evguenia Kouranova, C Frederick Lo, Helen K Warwick, Robert H Ring, Yolanda Kirksey, Suzan Aschmies, Jane Xu, Katie Kubek, Warren D Hirst, Catherine Gonzales, Yi Chen, Erin Murphy, Sarah Leonard, Dmytro Vasylyev, Aram Oganesian, Robert L Martone, Menelas N