日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A phase 2 trial of burosumab for treatment of fibroblast growth factor-23-mediated hypophosphatemia in children and adults with fibrous dysplasia

一项针对纤维性骨发育不良患儿和成人中成纤维细胞生长因子-23介导的低磷血症的布罗索单抗二期临床试验

de Jong, Olivia; Gun, Zubeyir Hasan; Asante-Otoo, Afua; Elbashir, Ibrahim I; Li, Xiaobai; Saboury, Babak; Kram, Vardit; de Castro, Luis F; MacDonald, Vivian; Boyce, Alison M

Single-cell analysis of human fibrous dysplasia bone reveals a fibrotic transcriptome and GNAS variants in endothelial, perivascular, and stromal cells

对人类纤维性骨发育不良的单细胞分析揭示了内皮细胞、血管周围细胞和基质细胞中存在的纤维化转录组和GNAS变异。

Wentworth, Kelly L; Fierro, Fernando A; Moody, Tania A; Le, Bryan; Michel, Zachary; Boyce, Alison; Collins, Michael; Kram, Vardit; de Castro, Luis F; Chow, Eric D; Qorbani, Amir; Hsiao, Edward C

A phase 2 trial of burosumab for treatment of fibroblast growth factor-23 mediated hypophosphatemia in children and adults with fibrous dysplasia

一项针对纤维性骨发育不良患儿和成人中成纤维细胞生长因子-23介导的低磷血症的布罗索单抗二期临床试验

de Jong, Olivia; Gun, Zubeyir Hasan; Asante-Otoo, Afua; Elbashir, Ibrahim; Li, Xiaobai; Saboury, Babak; Kram, Vardit; de Castro, Luis F; MacDonald, Vivian; Boyce, Alison M

Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier.

纤维蛋白是口腔黏膜屏障中中性粒细胞效应功能的关键调节因子

Silva Lakmali M, Doyle Andrew D, Greenwell-Wild Teresa, Dutzan Nicolas, Tran Collin L, Abusleme Loreto, Juang Lih Jiin, Leung Jerry, Chun Elizabeth M, Lum Andrew G, Agler Cary S, Zuazo Carlos E, Sibree Megan, Jani Priyam, Kram Vardit, Martin Daniel, Moss Kevin, Lionakis Michail S, Castellino Francis J, Kastrup Christian J, Flick Matthew J, Divaris Kimon, Bugge Thomas H, Moutsopoulos Niki M

Guidelines for Micro-Computed Tomography Analysis of Rodent Dentoalveolar Tissues

啮齿动物牙槽组织微型计算机断层扫描分析指南

Chavez, Michael B; Chu, Emily Y; Kram, Vardit; de Castro, Luis F; Somerman, Martha J; Foster, Brian L

OPG-Fc treatment partially rescues low bone mass phenotype in mature Bgn/Fmod deficient mice but is deleterious to the young mouse skeleton

OPG-Fc治疗可部分挽救成年Bgn/Fmod缺陷小鼠的低骨量表型,但对幼鼠骨骼有害。

Kram, Vardit; Jani, Priyam; Kilts, Tina M; Li, Li; Chu, Emily Y; Young, Marian F

Biglycan in the Skeleton

骷髅中的大狼

Kram, Vardit; Shainer, Reut; Jani, Priyam; Meester, Josephina A N; Loeys, Bart; Young, Marian F

Extracellular Matrix Mediates BMP-2 in a Model of Temporomandibular Joint Osteoarthritis.

细胞外基质介导 BMP-2 在颞下颌关节骨关节炎模型中的表达

Shirakura Maya, Kram Vardit, Robinson Jennifer, Sikka Sheena, Kilts Tina M, Wadhwa Sunil, Young Marian F

Biglycan potentially regulates angiogenesis during fracture repair by altering expression and function of endostatin

Biglycan可能通过改变内皮抑素的表达和功能来调节骨折修复过程中的血管生成。

Myren, Maja; Kirby, David J; Noonan, Megan L; Maeda, Azusa; Owens, Rick T; Ricard-Blum, Sylvie; Kram, Vardit; Kilts, Tina M; Young, Marian F

Oleoyl serine, an endogenous N-acyl amide, modulates bone remodeling and mass

油酰丝氨酸是一种内源性N-酰基酰胺,可调节骨骼重塑和骨量。

Smoum, Reem; Bar, Arik; Tan, Bo; Milman, Garry; Attar-Namdar, Malka; Ofek, Orr; Stuart, Jordyn M; Bajayo, Alon; Tam, Joseph; Kram, Vardit; O'Dell, David; Walker, Michael J; Bradshaw, Heather B; Bab, Itai; Mechoulam, Raphael