日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Fluorescence tracking Treg movement identifies anti-CCR8 and radiation as a therapeutic combination.

荧光追踪 Treg 的运动表明抗 CCR8 和放射疗法是一种有效的联合治疗方案。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.114572
Friedman David J, Ramin Sina, Blair Tiffany, Kramer Gwen, Bambina Shelly, Alice Alejandro F, Baird Jason, Medler Terry, Young Kristina H, Crittenden Marka R, Gough Michael J
IF
CCR8
T细胞
Treg
发表日期：2026
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Radiation therapy causes a STING and MyD88-independent upregulation of CD80 and CD86 in macrophages and monocytes that limits tumor control

放射疗法会导致巨噬细胞和单核细胞中CD80和CD86的表达上调，而这种上调不依赖于STING和MyD88，从而限制肿瘤控制。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-025-04272-0
Preet Kaur, Aanchal; Baird, Jason R; Alice, Alejandro F; Kramer, Gwen; Friedman, David; Moran, Eva; Crittenden, Marka; Gough, Michael J
巨噬细胞
肿瘤
T细胞
肿瘤免疫
巨噬细胞
STING
CD8
CD80
CD86
单核细胞
细胞生物学
免疫/内分泌
发表日期：2025
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TGFβ limits proximal CD8+ TCR signaling via PTPN22 following strong and moderate agonism

TGFβ 在强激动剂和中等激动剂作用后通过 PTPN22 限制近端 CD8+ TCR 信号传导

期刊:Journal of Immunology
影响因子:3.4
doi:10.1093/jimmun/vkaf216
Gunderson, Andrew J; Jordan, Kelley; Yamazaki, Tomoko; Raué, Hans-Peter; Kramer, Gwen; Fox, Nathaniel; Slifka, Mark K; Gough, Michael J; Crittenden, Marka R; Young, Kristina H
信号转导
T细胞
CD8
TGFβ
发表日期：2025
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ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control.

放射治疗后，T细胞上的ICOS表达上调，激动剂与放射治疗相结合可增强肿瘤控制

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-19256-8
Blair Tiffany, Baird Jason, Bambina Shelly, Kramer Gwen, Gostissa Monica, Harvey Christopher J, Gough Michael J, Crittenden Marka R
细胞生物学
肿瘤
T细胞
发表日期：2022
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STING expression and response to treatment with STING ligands in premalignant and malignant disease

STING表达及对STING配体治疗在癌前病变和恶性肿瘤中的作用

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0187532
Baird, Jason R; Feng, Zipei; Xiao, Hong D; Friedman, David; Cottam, Ben; Fox, Bernard A; Kramer, Gwen; Leidner, Rom S; Bell, R Bryan; Young, Kristina H; Crittenden, Marka R; Gough, Michael J
STING
肿瘤
肿瘤免疫
发表日期：2017
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Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy

肿瘤巨噬细胞上的Mertk是放射治疗后预防肿瘤复发的治疗靶点

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.11823
Crittenden, Marka R; Baird, Jason; Friedman, David; Savage, Talicia; Uhde, Lauren; Alice, Alejandro; Cottam, Benjamin; Young, Kristina; Newell, Pippa; Nguyen, Cynthia; Bambina, Shelly; Kramer, Gwen; Akporiaye, Emmanuel; Malecka, Anna; Jackson, Andrew; Gough, Michael J
巨噬细胞
肿瘤
肿瘤免疫
巨噬细胞
细胞生物学
Mer
免疫/内分泌
发表日期：2016
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Differential gene expression in primary human skin keratinocytes and fibroblasts in response to ionizing radiation.

电离辐射对原代人皮肤角质形成细胞和成纤维细胞差异基因表达的影响

期刊:Radiation Research
影响因子:2.7
doi:10.1667/RR1677.1
Warters Raymond L, Packard Ann T, Kramer Gwen F, Gaffney David K, Moos Philip J
细胞生物学
Human
发表日期：2009
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