日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EPHB4 is a therapeutic target in AML and promotes leukemia cell survival via AKT

EPHB4是急性髓系白血病(AML)的治疗靶点,它通过AKT促进白血病细胞存活。

Merchant, Akil A; Jorapur, Aparna; McManus, Amy; Liu, Ren; Krasnoperov, Valery; Chaudhry, Parvesh; Singh, Mohan; Harton, Lisa; Agajanian, Mary; Kim, Miriam; Triche, Timothy J Jr; Druker, Brian J; Tyner, Jeffrey W; Gill, Parkash S

The differential expression of EphB2 and EphB4 receptor kinases in normal bladder and in transitional cell carcinoma of the bladder.

正常膀胱和膀胱移行细胞癌中 EphB2 和 EphB4 受体激酶的差异表达

Li Xiuqing, Choi Wesley W, Yan Rui, Yu Haiyang, Krasnoperov Valery, Kumar S Ram, Schuckman Anne, Klumpp David J, Pan Chong-Xian, Quinn David, Gill Inderbir S, Gill Parkash S, Liu Ren

Converging evidence for efficacy from parallel EphB4-targeted approaches in ovarian carcinoma

来自平行 EphB4 靶向治疗卵巢癌的疗效证据不断汇聚

Spannuth, Whitney A; Mangala, Lingegowda S; Stone, Rebecca L; Carroll, Amy R; Nishimura, Masato; Shahzad, Mian M K; Lee, Sun-Joo; Moreno-Smith, Myrthala; Nick, Alpa M; Liu, Ren; Jennings, Nicholas B; Lin, Yvonne G; Merritt, William M; Coleman, Robert L; Vivas-Mejia, Pablo E; Zhou, Yue; Krasnoperov, Valery; Lopez-Berestein, Gabriel; Gill, Parkash S; Sood, Anil K

Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion.

抑制 Dll4 介导的信号传导会诱导未成熟血管增殖,导致组织灌注不良

Scehnet Jeffrey S, Jiang Weidong, Kumar S Ram, Krasnoperov Valery, Trindade Alexandre, Benedito Rui, Djokovic Dusan, Borges Cristina, Ley Eric J, Duarte Antonio, Gill Parkash S