日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

X-linked cancer-associated polypeptide (XCP) from lncRNA1456 modulates PHF8 histone demethylase activity to regulate the epigenome, gene expression, and cellular pathways in breast cancer

来自lncRNA1456的X染色体连锁癌症相关多肽(XCP)通过调节PHF8组蛋白去甲基化酶活性来调控乳腺癌的表观基因组、基因表达和细胞通路。

Gadad, Shrikanth S; Camacho, Cristel V; Gong, Xuan; Thornton, Micah; Malladi, Venkat S; Nagari, Anusha; Sundaresan, Aishwarya; Nandu, Tulip; Koul, Sneh; Peng, Yan; Kraus, W Lee

NAD(+) sensing by PARP7 regulates the C/EBPβ-dependent transcription program during adipogenesis.

PARP7 对 NAD(+) 的感知调节脂肪生成过程中 C/EBPβ 依赖的转录程序。

Stokes MiKayla S, Kim Yoon Jung, Kim Yonghyeon, Koul Sneh, Chiu Shu-Ping, Liu Chenqian, Dasovich Morgan, Zuniga Josue, Nandu Tulip, Huang Dan, Mathews Thomas P, Solmonson Ashley, Camacho Cristel V, Kraus W Lee

PARP16 is a Druggable Regulator of Ribosome MARylation and Protein Homeostasis in Ovarian Cancer Cells

PARP16是卵巢癌细胞中核糖体MARylation和蛋白质稳态的可药物调控因子

Challa, Sridevi; Dasovich, Morgan; Abshier, Jonathan C; Pekhale, Komal; Yang, Lu; Camacho, Cristel V; Kraus, W Lee

Comprehensive perturbation of transcription factors in human cardiomyocytes reveals the regulatory architecture of congenital heart disease

对人类心肌细胞中转录因子的全面扰动揭示了先天性心脏病的调控结构

Takeuchi, Chikara; Sivakumar, Sushama; Sundarrajan, Anjana; Wang, Yihan; Goetsch, Sean C; Zhao, Huan; Wang, Lei; Nzima, Mpathi; Deng, Minnie; Kulkarni, Kartik N; Xu, Lin; Wu, Jun; Posner, Bruce A; Chahrour, Maria H; Kraus, W Lee; Munshi, Nikhil V; Hon, Gary C

Ethanol induction of FGF21 in the liver is dependent on histone acetylation and ligand activation of ChREBP by glycerol-3-phosphate.

乙醇诱导肝脏中 FGF21 的产生依赖于组蛋白乙酰化和甘油-3-磷酸对 ChREBP 的配体激活

Cheong Mi Cheong, Mackowiak Bryan, Kim Hyung Bum, Hernandez Genaro, Nandu Tulip, Vale Kevin, Zhang Yuan, Zacharias Lauren G, Mathews Thomas P, Gao Bin, Kraus W Lee, Kliewer Steven A, Mangelsdorf David J

Benchmarking and optimizing Perturb-seq in differentiating human pluripotent stem cells

对 Perturb-seq 在分化人类多能干细胞中的应用进行基准测试和优化

Sivakumar, Sushama; Wang, Yihan; Goetsch, Sean C; Pandit, Vrushali; Wang, Lei; Zhao, Huan; Sundarrajan, Anjana; Armendariz, Daniel; Takeuchi, Chikara; Deng, Minnie; Nzima, Mpathi; Chen, Wei-Chen; Dederich, Ashley E; El Hayek, Lauretta; Gao, Taosha; Gogate, Ashlesha; Kaur, Kiran; Kim, Hyung Bum; McCoy, Melissa K; Niederstrasser, Hanspeter; Oura, Seiya; Pinzon-Arteaga, Carlos A; Sanghvi, Menaka; Schmitz, Daniel A; Yu, Leqian; Zhang, Yanfeng; Zhou, Qinbo; Kraus, W Lee; Xu, Lin; Wu, Jun; Posner, Bruce A; Chahrour, Maria H; Hon, Gary C; Munshi, Nikhil V

NAD (+) Sensing by PARP7 Regulates the C/EBPβ-Dependent Transcription Program in Adipose Tissue In Vivo

PARP7 对 NAD (+) 的感知在体内调节脂肪组织中 C/EBPβ 依赖性转录程序

Stokes, MiKayla S; Kim, Yoon Jung; Kim, Yonghyeon; Koul, Sneh; Chiu, Shu-Ping; Dasovich, Morgan; Zuniga, Josue; Nandu, Tulip; Huang, Dan; Mathews, Thomas P; Solmonson, Ashley; Camacho, Cristel V; Kraus, W Lee

Mapping the Subtype-Specific PARP1 ADP-ribosylated Proteome in Breast Cancer Cells.

绘制乳腺癌细胞中亚型特异性 PARP1 ADP 核糖基化蛋白质组图谱。

Koul Sneh, Kwon Minjung, Tapadar Poulami, Dai Yangyang, Nandu Tulip, Huang Dan, Camacho Cristel V, Kraus W Lee

Role of Macrophage PARP1 in the Regulation of Crosstalk between Adipose Immune Cells and Adipocytes during Diet-induced Obesity.

巨噬细胞 PARP1 在饮食诱导肥胖期间调节脂肪免疫细胞与脂肪细胞之间相互作用中的作用

Zhu Jingbo, Gupte Rebecca, Nandu Tulip, Huang Kai, Kraus W Lee, Huang Dan

Estrogen Receptor Enhancers Sensitive to Low Doses of Hormone Specify Distinct Molecular and Biological Outcomes.

对低剂量激素敏感的雌激素受体增强剂可产生独特的分子和生物学结果

Kim Hyung Bum, Nandu Tulip, Camacho Cristel V, Kraus W Lee