ERK signaling controls productive HIF-1 binding to chromatin and cancer cell adaptation to hypoxia through HIF-1α interaction with NPM1
ERK信号通路通过HIF-1α与NPM1的相互作用，控制HIF-1与染色质的有效结合以及癌细胞对缺氧的适应。
期刊:Molecular Oncology
影响因子:4.5
doi:10.1002/1878-0261.13080
Koukoulas, Kreon; Giakountis, Antonis; Karagiota, Angeliki; Samiotaki, Martina; Panayotou, George; Simos, George; Mylonis, Ilias
肿瘤
肿瘤免疫
信号转导
MAPK/ERK
NPM
细胞生物学
