日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites.

多不饱和脂肪酸通过两个结合位点之一抑制五聚体配体门控离子通道

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.74306
Dietzen Noah M, Arcario Mark J, Chen Lawrence J, Petroff John T 2nd, Moreland K Trent, Krishnan Kathiresan, Brannigan Grace, Covey Douglas F, Cheng Wayland Wl
信号转导
发表日期：2022
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The T-type calcium channel isoform Ca(v)3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile

T型钙通道亚型Ca(v)3.1是麻醉性神经甾体(3β,5β,17β)-3-羟基雄甾烷-17-腈催眠作用的靶点

期刊:British Journal of Anaesthesia
影响因子:9.2
doi:10.1016/j.bja.2020.07.022
Timic Stamenic, Tamara; Feseha, Simon; Manzella, Francesca M; Wallace, Damon; Wilkey, Davis; Corrigan, Timothy; Fiedler, Hanna; Doerr, Patricia; Krishnan, Kathiresan; Raol, Yogendra H; Covey, Douglas F; Jevtovic-Todorovic, Vesna; Todorovic, Slobodan M
发表日期：2021
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Differential effects of the novel neurosteroid hypnotic (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile on electroencephalogram activity in male and female rats

新型神经甾体催眠药(3β,5β,17β)-3-羟基雄甾烷-17-腈对雄性和雌性大鼠脑电图活动的差异性影响

期刊:British Journal of Anaesthesia
影响因子:9.2
doi:10.1016/j.bja.2021.03.029
Joksimovic, Srdjan M; Sampath, Dayalan; Krishnan, Kathiresan; Covey, Douglas F; Jevtovic-Todorovic, Vesna; Raol, Yogendra H; Todorovic, Slobodan M
Rat
神经科学
发表日期：2021
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Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells

活细胞内溶酶体与线粒体之间甾醇转移的膜接触位点的定量成像

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-021-87876-7
Juhl, Alice Dupont; Heegaard, Christian W; Werner, Stephan; Schneider, Gerd; Krishnan, Kathiresan; Covey, Douglas F; Wüstner, Daniel
细胞生物学
线粒体
发表日期：2021
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Validation of Trifluoromethylphenyl Diazirine Cholesterol Analogues As Cholesterol Mimetics and Photolabeling Reagents

三氟甲基苯基重氮丙烯胆固醇类似物作为胆固醇模拟物和光标记试剂的验证

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.1c00364
Krishnan, Kathiresan; Qian, Mingxing; Feltes, McKenna; Chen, Zi-Wei; Gale, Sarah; Wang, Lei; Sugasawa, Yusuke; Reichert, David E; Schaffer, Jean E; Ory, Daniel S; Evers, Alex S; Covey, Douglas F
代谢
发表日期：2021
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Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels

神经活性类固醇鞘内注射对啮齿动物术后疼痛模型的预防性镇痛作用：T型钙通道作用的证据

期刊:Cells
影响因子:5.2
doi:10.3390/cells9122674
Tat, Quy L; Joksimovic, Srdjan M; Krishnan, Kathiresan; Covey, Douglas F; Todorovic, Slobodan M; Jevtovic-Todorovic, Vesna
发表日期：2020
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Novel neurosteroid hypnotic blocks T-type calcium channel-dependent rebound burst firing and suppresses long-term potentiation in the rat subiculum

新型神经甾体催眠药阻断大鼠下托中T型钙通道依赖性反弹爆发放电，并抑制长时程增强作用

期刊:British Journal of Anaesthesia
影响因子:9.2
doi:10.1016/j.bja.2019.01.029
Joksimovic, Srdjan M; Izumi, Yukitoshi; Joksimovic, Sonja Lj; Tesic, Vesna; Krishnan, Kathiresan; Asnake, Betelehem; Jevtovic-Todorovic, Vesna; Covey, Douglas F; Zorumski, Charles F; Todorovic, Slobodan M
Rat
发表日期：2019
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Multiple functional neurosteroid binding sites on GABAA receptors

GABAA受体上存在多个功能性神经甾体结合位点

期刊:PLoS Biology
影响因子:7.8
doi:10.1371/journal.pbio.3000157
Zi-Wei Chen,John R Bracamontes,Melissa M Budelier,Allison L Germann,Daniel J Shin,Krishnan Kathiresan,Ming-Xing Qian,Brad Manion,Wayland W L Cheng,David E Reichert,Gustav Akk,Douglas F Covey,Alex S Evers
神经科学
发表日期：2019
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Visualizing pregnenolone sulfate-like modulators of NMDA receptor function reveals intracellular and plasma-membrane localization

可视化孕烯醇酮硫酸酯样NMDA受体功能调节剂揭示了其细胞内和质膜定位

期刊:Neuropharmacology
影响因子:4.6
doi:10.1016/j.neuropharm.2018.10.015
Chisari, Mariangela; Wilding, Timothy J; Brunwasser, Samuel; Krishnan, Kathiresan; Qian, Mingxing; Benz, Ann; Huettner, James E; Zorumski, Charles F; Covey, Douglas F; Mennerick, Steven
信号转导
细胞生物学
发表日期：2019
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Common binding sites for cholesterol and neurosteroids on a pentameric ligand-gated ion channel

胆固醇和神经甾体在五聚体配体门控离子通道上的共同结合位点

期刊:Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids
影响因子:3.3
doi:10.1016/j.bbalip.2018.11.005
Budelier, Melissa M; Cheng, Wayland W L; Chen, Zi-Wei; Bracamontes, John R; Sugasawa, Yusuke; Krishnan, Kathiresan; Mydock-McGrane, Laurel; Covey, Douglas F; Evers, Alex S
代谢
发表日期：2019
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