日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mono- and multimeric PSMA-targeting small molecule-thorium-227 conjugates for optimized efficacy and biodistribution in preclinical models

单体和多聚体PSMA靶向小分子-钍-227偶联物在临床前模型中优化疗效和生物分布

Böhnke, Niels; Indrevoll, Bård; Hammer, Stefanie; Papple, Alex; Kristian, Alexander; Briem, Hans; Celik, Arif; Mumberg, Dominik; Cuthbertson, Alan; Zitzmann-Kolbe, Sabine

The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy

SRC家族是三阴性乳腺癌(对化疗产生耐药性)的治疗靶点。

Egeland, Eivind Valen; Seip, Kotryna; Skourti, Eleni; Øy, Geir Frode; Pettersen, Solveig J; Pandya, Abhilash D; Dahle, Maria A; Haugen, Mads H; Kristian, Alexander; Nakken, Sigve; Engebraaten, Olav; Mælandsmo, Gunhild M; Prasmickaite, Lina

A Targeted Thorium-227 Conjugate Demonstrates Efficacy in Preclinical Models of Acquired Drug Resistance and Combination Potential with Chemotherapeutics and Antiangiogenic Therapies.

靶向钍-227偶联物在获得性耐药的临床前模型中显示出疗效,并具有与化疗药物和抗血管生成疗法联合应用的潜力

Zitzmann-Kolbe Sabine, Kristian Alexander, Zopf Dieter, Kamfenkel Claudia, Politz Oliver, Ellingsen Christine, Hilbig Jochen, Juul Mark U, Fonslet Jesper, Nielsen Carsten H, Schatz Christoph A, Bjerke Roger M, Cuthbertson Alan S, Mumberg Dominik, Hagemann Urs B

Efficacy of a HER2-Targeted Thorium-227 Conjugate in a HER2-Positive Breast Cancer Bone Metastasis Model

HER2靶向钍-227偶联物在HER2阳性乳腺癌骨转移模型中的疗效

Karlsson, Jenny; Hagemann, Urs B; Cruciani, Véronique; Schatz, Christoph A; Grant, Derek; Ellingsen, Christine; Kristian, Alexander; Katoozi, Shirin; Mihaylova, Dessislava; Uran, Steinar R; Suominen, Mari; Bjerke, Roger M; Ryan, Olav B; Cuthbertson, Alan

Tumor growth inhibition and immune system activation following treatment with thorium-227 conjugates and PD-1 check-point inhibition in the MC-38 murine model

在MC-38小鼠模型中,使用钍-227偶联物和PD-1检查点抑制剂治疗后,肿瘤生长受到抑制,免疫系统被激活。

Berg-Larsen, Axel; Mobergslien, Anne; Moen, Ingrid; Petros, Gebregziabher; Kristian, Alexander; Gunvaldsen, Kristine Sponheim; Cruciani, Véronique; Wickstroem, Katrine; Bjerke, Roger Malerbakken; Karlsson, Jenny; Cuthbertson, Alan