The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts
INSIG2上游的SNP与体重指数的关联在多个队列中得到证实,但并非所有队列都证实了这一点。
期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.0030061
Lyon, Helen N; Emilsson, Valur; Hinney, Anke; Heid, Iris M; Lasky-Su, Jessica; Zhu, Xiaofeng; Thorleifsson, Gudmar; Gunnarsdottir, Steinunn; Walters, G Bragi; Thorsteinsdottir, Unnur; Kong, Augustine; Gulcher, Jeffrey; Nguyen, Thuy Trang; Scherag, André; Pfeufer, Arne; Meitinger, Thomas; Brönner, Günter; Rief, Winfried; Soto-Quiros, Manuel E; Avila, Lydiana; Klanderman, Barbara; Raby, Benjamin A; Silverman, Edwin K; Weiss, Scott T; Laird, Nan; Ding, Xiao; Groop, Leif; Tuomi, Tiinamaija; Isomaa, Bo; Bengtsson, Kristina; Butler, Johannah L; Cooper, Richard S; Fox, Caroline S; O'Donnell, Christopher J; Vollmert, Caren; Celedón, Juan C; Wichmann, H Erich; Hebebrand, Johannes; Stefansson, Kari; Lange, Christoph; Hirschhorn, Joel N