日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

X-ray crystal structure localizes the mechanism of inhibition of an IL-36R antagonist monoclonal antibody to interaction with Ig1 and Ig2 extra cellular domains

X射线晶体结构揭示了IL-36R拮抗剂单克隆抗体抑制Ig1和Ig2胞外结构域相互作用的机制

Larson, Eric T; Brennan, Debra L; Hickey, Eugene R; Ganesan, Raj; Kroe-Barrett, Rachel; Farrow, Neil A

Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA expression data (FANTOM5).

使用大鼠抗小鼠 IL-36R 单克隆抗体和 RNA 表达数据 (FANTOM5) 对抗 IL-36R 单克隆抗体 MAB92 的人体药代动力学进行基于模型的预测的回顾性分析

Ahlberg Jennifer, Giragossian Craig, Li Hua, Myzithras Maria, Raymond Ernie, Caviness Gary, Grimaldi Christine, Brown Su-Ellen, Perez Rocio, Yang Danlin, Kroe-Barrett Rachel, Joseph David, Pamulapati Chandrasena, Coble Kelly, Ruus Peter, Woska Joseph R, Ganesan Rajkumar, Hansel Steven, Mbow M Lamine

IgG cooperativity - Is there allostery? Implications for antibody functions and therapeutic antibody development

IgG协同性——是否存在变构效应?对抗体功能和治疗性抗体研发的影响

Yang, Danlin; Kroe-Barrett, Rachel; Singh, Sanjaya; Roberts, Christopher J; Laue, Thomas M

Selective targeting of the IL23 pathway: Generation and characterization of a novel high-affinity humanized anti-IL23A antibody

选择性靶向IL23通路:新型高亲和力人源化抗IL23A抗体的制备和表征

Singh, Sanjaya; Kroe-Barrett, Rachel R; Canada, Keith A; Zhu, Xiang; Sepulveda, Eliud; Wu, Helen; He, Yaqin; Raymond, Ernest L; Ahlberg, Jennifer; Frego, Lee E; Amodeo, Laura M; Catron, Katrina M; Presky, David H; Hanke, Jeffrey H