日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intellectual disability risk gene RFX4 regulates cortical neurogenesis by restraining neuronal differentiation

智力障碍风险基因RFX4通过抑制神经元分化来调控皮层神经发生。

Determan, Julianna J; Chapman, Gareth; Crump, Sydney R; Batool, Faiza; Malik, Sofia; Gujral, Taran; Buchser, William; Valentine, Caleb; Elia, Serena; Sentmanat, Monica; Cui, Xiaoxia; Jetter, Haley; Kroll, Kristen L

Autism- and intellectual disability-associated MYT1L mutation alters human cortical interneuron differentiation, maturation, and physiology.

与自闭症和智力障碍相关的 MYT1L 突变会改变人类皮层中间神经元的分化、成熟和生理功能

Prakasam Ramachandran, Determan Julianna, Chapman Gareth, Narasimhan Mishka, Shen Renata, Saleh Maamoon, Kaushik Komal, Gontarz Paul, Meganathan Kesavan, Hakim Bilal, Zhang Bo, Huettner James E, Kroll Kristen L

Lifespan in rodents with MYT1L heterozygous mutation

携带MYT1L杂合突变的啮齿动物的寿命

Schreiber, Allyson; Swift, Raylynn G; Wilson, Leslie; Kroll, Kristen L; Dougherty, Joseph D; Maloney, Susan E

A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female mice

一项针对下丘脑表型的研究揭示了MYT1L单倍体不足在雄性和雌性小鼠中的分子和行为后果。

Maloney, Susan E; McCullough, Katherine B; Chaturvedi, Sneha M; Selmanovic, Din; Chase, Rebecca; Chen, Jiayang; Wu, Shanyun; Granadillo, Jorge L; Kroll, Kristen L; Dougherty, Joseph D

Tatton-Brown-Rahman-Syndrome-associated DNMT3A mutations de-repress cortical interneuron differentiation to disrupt neuronal network function

Tatton-Brown-Rahman综合征相关的DNMT3A突变会解除对皮质中间神经元分化的抑制,从而破坏神经元网络功能。

Chapman, Gareth; Determan, Julianna; Edwards, John R; Batool, Faiza; Huettner, James E; Prakasam, Ramachandran; Crump, Sydney R; Jetter, Haley; Gabel, Harrison W; Kroll, Kristen L

Neurobehavioral Profiles and Clinical Consequences of MYT1L-Related Neurodevelopmental Disorder: Insights from the Brain Gene Registry

MYT1L相关神经发育障碍的神经行为特征和临床后果:来自脑基因登记库的启示

Granadillo, Jorge L; Kaster, Levi; Grewal, Daleep; Schreiber, Allyson; Abbacchi, Anna M; Lanzotti, Virginia; Gupta, Aditi; Gurnett, Christina A; Kroll, Kristen L; Dougherty, Joseph D

A single binge ethanol exposure is apoptotic within hours across neurodevelopment and partially regulated by the Myt1l gene

在神经发育过程中,单次大量摄入乙醇会在数小时内导致细胞凋亡,并且部分受Myt1l基因调控。

Fuhler, Nicole; Palmer, Cory; Tunzi, Gianna; Tian, Lilly; Fotedar, Maya; Chase, Rebecca; Prakasam, Ramachandran; Maloney, Susan E; Neblock, C Eric; Chen, Jiayang; Kroll, Kristen L; Dougherty, Joseph D; Noguchi, Kevin K

Duplication Versus Deletion Through the Lens of 15q13.3: Clinical and Research Implications of Studying Copy Number Variants Associated with Neuropsychiatric Disorders in Induced Pluripotent Stem Cell-Derived Neurons

从15q13.3的角度探讨重复与缺失:研究诱导多能干细胞衍生神经元中与神经精神疾病相关的拷贝数变异的临床和研究意义

Antony, Irene; Narasimhan, Mishka; Shen, Renata; Prakasam, Ramachandran; Kaushik, Komal; Chapman, Gareth; Kroll, Kristen L

Can the "female protective effect" liability threshold model explain sex differences in autism spectrum disorder?

“女性保护效应”责任阈值模型能否解释自闭症谱系障碍中的性别差异?

Dougherty, Joseph D; Marrus, Natasha; Maloney, Susan E; Yip, Benjamin; Sandin, Sven; Turner, Tychele N; Selmanovic, Din; Kroll, Kristen L; Gutmann, David H; Constantino, John N; Weiss, Lauren A

Epigenetic regulation during human cortical development: Seq-ing answers from the brain to the organoid

人类皮层发育过程中的表观遗传调控:从大脑到类器官的测序答案

Lewis, Emily M A; Kaushik, Komal; Sandoval, Luke A; Antony, Irene; Dietmann, Sabine; Kroll, Kristen L