日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Second-Generation AURKA-Targeting PROTACs: Structural Optimization toward in Vivo Degradation in Neuroblastoma

第二代靶向AURKA的PROTAC:针对神经母细胞瘤体内降解的结构优化

Krols, Simon; Rishfi, Muhammad; Martens, Fien; Van Hauwermeiren, Anouk; Sanders, Ellen; De Sutter, Pieter-Jan; Vermeulen, An; De Wever, Kaat; Bekaert, Sarah-Lee; Dolman, M Emmy M; Tax, Gabor; Kamili, Alvin; Fletcher, Jamie I; Depestel, Lisa; De Wilde, Bram; Durinck, Kaat; Van Calenbergh, Serge

Dual N(6)/C7-Substituted 7-Deazapurine and Tricyclic Ribonucleosides with Affinity for G Protein-Coupled Receptors

对 G 蛋白偶联受体具有亲和力的双 N(6)/C7 取代的 7-脱氮嘌呤和三环核糖核苷

Krols, Simon; Matteucci, Federica; Van Hecke, Kristof; Caljon, Guy; Jacobson, Kenneth A; Van Calenbergh, Serge

The curious case of the Dana platypus and what it can teach us about how lead shotgun pellets behave in fluid preserved museum specimens and may limit their scientific value

达纳鸭嘴兽的奇特案例及其对铅弹在液体保存的博物馆标本中的行为及其可能限制其科学价值的启示

Lauridsen, Henrik; Johansson, Daniel Klingberg; Pedersen, Christina Carøe Ejlskov; Hansen, Kasper; Krols, Michiel; Gregersen, Kristian Murphy; Jæger, Julie Nogel; Williams, Catherine Jane Alexandra; Sandgreen, Ditte-Mari; Alstrup, Aage Kristian Olsen; Bertelsen, Mads Frost; Møller, Peter Rask

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

ESYT1 将内质网与线粒体连接起来,是线粒体脂质和钙稳态所必需的

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control

MIRO 和 DRP1 驱动线粒体衍生的囊泡生物合成并促进质量控制

Tim König, Hendrik Nolte, Mari J Aaltonen, Takashi Tatsuta, Michiel Krols, Thomas Stroh, Thomas Langer, Heidi M McBride

Sensory neuropathy-causing mutations in ATL3 affect ER-mitochondria contact sites and impair axonal mitochondrial distribution

ATL3基因中导致感觉神经病变的突变会影响内质网-线粒体接触位点,并损害轴突线粒体的分布。

Krols, Michiel; Asselbergh, Bob; De Rycke, Riet; De Winter, Vicky; Seyer, Alexandre; Müller, Franz-Josef; Kurth, Ingo; Bultynck, Geert; Timmerman, Vincent; Janssens, Sophie

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis

HSPB1 促进 ERK 介导的 BIM 磷酸化和降解,从而减轻内质网应激诱导的细胞凋亡

Donna Kennedy, Katarzyna Mnich, Deepu Oommen, Reka Chakravarthy, Leonardo Almeida-Souza, Michiel Krols, Svetlana Saveljeva, Karen Doyle, Sanjeev Gupta, Vincent Timmerman, Sophie Janssens, Adrienne M Gorman, Afshin Samali

Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues

高效发散合成新型免疫刺激剂4″-修饰的α-半乳糖基神经酰胺类似物

Janssens, Jonas; Decruy, Tine; Venken, Koen; Seki, Toshiyuki; Krols, Simon; Van der Eycken, Johan; Tsuji, Moriya; Elewaut, Dirk; Van Calenbergh, Serge

Mitochondria-associated membranes as hubs for neurodegeneration

线粒体相关膜作为神经退行性疾病的枢纽

Krols, Michiel; van Isterdael, Gert; Asselbergh, Bob; Kremer, Anna; Lippens, Saskia; Timmerman, Vincent; Janssens, Sophie

ER-Mitochondria contact sites: A new regulator of cellular calcium flux comes into play

内质网-线粒体接触位点:细胞钙流的新调节因子发挥作用

Krols, Michiel; Bultynck, Geert; Janssens, Sophie