日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structure-guided design of a methyltransferase-like 3 (METTL3) proteolysis targeting chimera (PROTAC) incorporating an indole-nicotinamide chemotype.

结构导向设计甲基转移酶样 3 (METTL3) 蛋白水解靶向嵌合体 (PROTAC)，其中包含吲哚-烟酰胺化学类型

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d5md00359h
Weldert Annabelle C, Frey Ariane F, Krone Mackenzie W, Krähe Franziska, Kuhn Hannah, Kersten Christian, Barthels Fabian
免疫/内分泌
发表日期：2025
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Targeted Degradation of mRNA Decapping Enzyme DcpS by a VHL-Recruiting PROTAC

通过 VHL 募集 PROTAC 靶向降解 mRNA 脱帽酶 DcpS

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.2c00145
Swartzel, Jake C; Bond, Michael J; Pintado-Urbanc, Andreas P; Daftary, Mehana; Krone, Mackenzie W; Douglas, Todd; Carder, Evan J; Zimmer, Joshua T; Maeda, Takahiro; Simon, Matthew D; Crews, Craig M
VHL
发表日期：2022
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More Than π-π-π Stacking: Contribution of Amide-π and CH-π Interactions to Crotonyllysine Binding by the AF9 YEATS Domain

超越π-π-π堆积：酰胺-π和CH-π相互作用对AF9 YEATS结构域与巴豆酰赖氨酸结合的贡献

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.0c06568
Krone, Mackenzie W; Travis, Christopher R; Lee, Ga Young; Eckvahl, Hannah J; Houk, K N; Waters, Marcey L
AF9
发表日期：2020
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Thermodynamic consequences of Tyr to Trp mutations in the cation-π-mediated binding of trimethyllysine by the HP1 chromodomain

Tyr 突变为 Trp 对 HP1 染色质结构域介导的三甲基赖氨酸阳离子-π 结合的热力学影响

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d0sc00227e
Krone, Mackenzie W; Albanese, Katherine I; Leighton, Gage O; He, Cyndi Qixin; Lee, Ga Young; Garcia-Borràs, Marc; Guseman, Alex J; Williams, David C Jr; Houk, K N; Brustad, Eric M; Waters, Marcey L
发表日期：2020
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Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis

通过非天然氨基酸诱变研究HP1染色质结构域与三甲基赖氨酸的结合

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.7b09223
Baril, Stefanie A; Koenig, Amber L; Krone, Mackenzie W; Albanese, Katherine I; He, Cyndi Qixin; Lee, Ga Young; Houk, Kendall N; Waters, Marcey L; Brustad, Eric M
发表日期：2017
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