日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Isolation and structure elucidation of Dm-CVNH, a new cyanovirin-N homolog with activity against SARS-CoV-2 and HIV-1.

从 SARS-CoV-2 和 HIV-1 中分离和解析出新型氰基病毒素-N 同系物 Dm-CVNH 的结构

Orfanoudaki Maria, Krumpe Lauren R H, Shenoy Shilpa R, Wilson Jennifer, Guszczynski Tad, Henrich Curtis J, Temme J Sebastian, Gildersleeve Jeffrey C, Molina-Molina Elisa, Erkizia Itziar, Blanco JuliÃ, Izquierdo-Useros Nuria, Montiero Fabio, Tanuri Amilcar, Rech Elibio, O'Keefe Barry R

Picking the tyrosine-lock: chemical synthesis of the tyrosyl-DNA phosphodiesterase I inhibitor recifin A and analogues

破解酪氨酸锁:酪氨酰-DNA磷酸二酯酶I抑制剂recifin A及其类似物的化学合成

Smallwood, Taylor B; Krumpe, Lauren R H; Payne, Colton D; Klein, Victoria G; O'Keefe, Barry R; Clark, Richard J; Schroeder, Christina I; Rosengren, K Johan

MoMo30 Binds to SARS-CoV-2 Spike Variants and Blocks Infection by SARS-CoV-2 Pseudovirus

MoMo30 与 SARS-CoV-2 刺突蛋白变体结合并阻断 SARS-CoV-2 假病毒感染

Kenya DeBarros, Mahfuz Khan, Morgan Coleman, Vincent C Bond, Virginia Floyd, Erick Gbodossou, Amad Diop, Lauren R H Krumpe, Barry R O'Keefe, Michael D Powell

An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics

一种利用无细胞系统快速分布式生产广谱抗病毒格里菲辛以缓解流行病的方法

Shayan G Borhani, Max Z Levine, Lauren H Krumpe, Jennifer Wilson, Curtis J Henrich, Barry R O'Keefe, Donald C Lo, G Sitta Sittampalam, Alexander G Godfrey, R Dwayne Lunsford, Venkata Mangalampalli, Dingyin Tao, Christopher A LeClair, Aaron P Thole, Douglas Frey, James Swartz, Govind Rao

Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2

Cyanovirin-N 与受体结合域之外的 SARS-CoV-2 刺突寡糖结合,阻断 SARS-CoV-2 感染

Jordana Muñoz-Basagoiti, Fábio Luís Lima Monteiro, Lauren R H Krumpe, Victoria Armario-Najera, Shilpa R Shenoy, Daniel Perez-Zsolt, Harrison James Westgarth, Gemma Villorbina, Larissa Maciel Bomfim, Dàlia Raïch-Regué, Lara Nogueras, Curtis J Henrich, Marçal Gallemí, Filipe Romero Rebello Moreira, Pa

X-ray quasi-periodic eruptions from two previously quiescent galaxies

来自两个先前处于静止状态的星系的X射线准周期性爆发

Arcodia, R; Merloni, A; Nandra, K; Buchner, J; Salvato, M; Pasham, D; Remillard, R; Comparat, J; Lamer, G; Ponti, G; Malyali, A; Wolf, J; Arzoumanian, Z; Bogensberger, D; Buckley, D A H; Gendreau, K; Gromadzki, M; Kara, E; Krumpe, M; Markwardt, C; Ramos-Ceja, M E; Rau, A; Schramm, M; Schwope, A

The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation

天然产物丁基环庚基 Prodiginine 可与 Pre-miR-21 结合,抑制 Dicer 介导的 Pre-miR-21 加工,并阻止细胞增殖

Joe S Matarlo, Lauren R H Krumpe, William F Heinz, Daniel Oh, Shilpa R Shenoy, Cheryl L Thomas, Ekaterina I Goncharova, Stephen J Lockett, Barry R O'Keefe

Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities

真菌 Dictyosporium sp. 的次级代谢产物及其 MALT1 抑制活性

Trong D Tran, Brice A P Wilson, Curtis J Henrich, Louis M Staudt, Lauren R H Krumpe, Emily A Smith, Jarrod King, Karen L Wendt, Alberto M Stchigel, Andrew N Miller, Robert H Cichewicz, Barry R O'Keefe, Kirk R Gustafson

Gene-silencing suppressors for high-level production of the HIV-1 entry inhibitor griffithsin in Nicotiana benthamiana

本氏烟草中用于高水平产生 HIV-1 进入抑制剂 griffithsin 的基因沉默抑制因子

Habibi, Peyman; Soccol, Carlos Ricardo; O'Keefe, Barry R; Krumpe, Lauren R H; Wilson, Jennifer; de Macedo, Leonardo Lima Pepino; Faheem, Muhammad; Dos Santos, Vanessa Olinto; Prado, Guilherme Souza; Botelho, Marco Antonio; Lacombe, Severine; Grossi-de-Sa, Maria Fatima

Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)

抑制人类酪氨酰 DNA 磷酸二酯酶 (TDP1) 催化功能的天然产物的鉴定

Alun Bermingham, Edmund Price, Christophe Marchand, Adel Chergui, Alena Naumova, Emily L Whitson, Lauren R H Krumpe, Ekaterina I Goncharova, Jason R Evans, Tawnya C McKee, Curtis J Henrich, Yves Pommier, Barry R O'Keefe