日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Modified protein selection strategy based on Escherichia coli's Hitchhiker transport and validation through selection of nanobodies targeting bovine interferon gamma

基于大肠杆菌Hitchhiker转运的改良型蛋白质选择策略,并通过筛选靶向牛干扰素γ的纳米抗体进行验证

Sirimanakul, Suwitchaya; Hurley, Joseph D; Thaiprayoon, Apisitt; Intasurat, Kwanpet; Kasemsukwimol, Warisara; Submunkongtawee, Nonth; Tabtimmai, Lueacha; Jaengwang, Kittitat; Choowongkomon, Kiattawee; Riangrungroj, Pinpunya; Leelawattanachai, Jeerapond; Kruse, Andrew C; Packthongsuk, Kreeson; Waraho-Zhmayev, Dujduan

Development of nanobody-conjugated LL37 for synergistic therapy against MDR Acinetobacter baumannii

开发纳米抗体偶联LL37用于对抗耐多药鲍曼不动杆菌的协同治疗

Thaiprayoon, Apisitt; Oonanant, Worrapoj; Boonsilp, Siriphan; Submunkongtawee, Nonth; Longsompurana, Phoomintara; Moonmangmee, Duangtip; Riangrungroj, Pinpunya; Leelawattanachai, Jeerapond; Tabtimmai, Lueacha; Kruse, Andrew C; DeLisa, Matthew P; Havanapan, Phattara-Orn; Waraho-Zhmayev, Dujduan

Isolation of Antigen-Specific Nanobodies From Synthetic Libraries Using a Protein Selection Strategy That Combines MACS-Based Screening of YSD and FLI-TRAP.

利用结合 MACS 筛选 YSD 和 FLI-TRAP 的蛋白质选择策略,从合成库中分离抗原特异性纳米抗体。

Thaiprayoon Apisitt, Chantarasorn Yodpong, Oonanant Worrapoj, Kasorn Anongnard, Longsompurana Phoomintara, Tapaneeyakorn Satita, Riangrungroj Pinpunya, Loison Fabien, Kruse Andrew C, DeLisa Matthew P, Waraho-Zhmayev Dujduan

Machine learning enables efficient and effective affinity maturation of nanobodies

机器学习能够实现纳米抗体的高效亲和力成熟

Paul, Steffanie; Harvey, Edward P; Osei-Owusu, James; Kollasch, Aaron W; Riesselman, Adam J; McMahon, Conor; Gazizov, Artem; Anuganti, Murali; Belay, Filmawit; Kieu, Minh Anh; Zhu, Haisun; Hollingsworth, L Robert; Harper, J Wade; Moshinsky, Deborah J; Teixeira, Andre A R; Marks, Debora S; Kruse, Andrew C

A DNA-gated molecular guard controls bacterial Hailong anti-phage defence.

DNA门控分子守卫控制细菌海龙噬菌体防御

Tan Joel M J, Melamed Sarah, Cofsky Joshua C, Syangtan Deepsing, Hobbs Samuel J, Del Mármol Josefina, Jost Marco, Kruse Andrew C, Sorek Rotem, Kranzusch Philip J

The hit-and-run of cell wall synthesis: LpoB transiently binds and activates PBP1b through a conserved allosteric switch

细胞壁合成的“速战速决”:LpoB 通过保守的变构开关瞬时结合并激活 PBP1b。

Shlosman, Irina; Vettiger, Andrea; Bernhardt, Thomas G; Kruse, Andrew C; Loparo, Joseph J

Conformational regulation of two essential activators of bacterial cell elongation

细菌细胞伸长两个关键激活因子的构象调控

Gilman, Morgan S A; Shlosman, Irina; Guerra, Daniel D Samé; Domecillo, Masy; Fivenson, Elayne M; Bourett, Claire; Bernhardt, Thomas G; Polizzi, Nicholas F; Loparo, Joseph J; Kruse, Andrew C

Epitope-directed selection of GPCR nanobody ligands with evolvable function.

表位导向筛选具有可进化功能的GPCR纳米抗体配体

Skiba Meredith A, Canavan Clare, Nemeth Genevieve R, Liu Jinghan, Kanso Ali, Kruse Andrew C

Isolation of PCSK9-specific nanobodies from synthetic libraries using a combined protein selection strategy

利用组合蛋白筛选策略从合成文库中分离PCSK9特异性纳米抗体

Thaiprayoon, Apisitt; Chantarasorn, Yodpong; Oonanant, Worrapoj; Kasorn, Anongnard; Longsompurana, Phoomintara; Tapaneeyakorn, Satita; Riangrungroj, Pinpunya; Loison, Fabien; Kruse, Andrew C; DeLisa, Matthew P; Waraho-Zhmayev, Dujduan

G Protein Selectivity in Dopamine Receptors is Determined before GDP Release

多巴胺受体中G蛋白的选择性在GDP释放之前就已决定

Tawfeeq, Caesar; Hilibrand, Ari S; Smith, Jeffrey S; Portillo, Jennifer; Kruse, Andrew C; Abrol, Ravinder