日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Perimetry of the Central Visual Field Using a Head-Mounted Open-Source Perimeter in Patients with Inherited Retinal Diseases

使用头戴式开源视野计对遗传性视网膜疾病患者进行中心视野检查

期刊:
影响因子:
doi:10.3390/vision10010012
Huchzermeyer, Cord; Kruse, Friedrich; Kremers, Jan
发表日期：2026
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Safety, tolerability and clinical effects of rovunaptabin, also known as BC007 on fatigue and quality of life in patients with Post-COVID syndrome (reCOVer): a prospective, exploratory, placebo-controlled, double-blind, randomised phase IIa clinical trial (RCT)

rovunaptabin（又名 BC007）对 COVID 后遗症患者疲劳和生活质量的安全性、耐受性和临床疗效 (reCOVer)：一项前瞻性、探索性、安慰剂对照、双盲、随机 IIa 期临床试验 (RCT)

期刊:EClinicalMedicine
影响因子:10
doi:10.1016/j.eclinm.2025.103358
Hohberger, Bettina; Ganslmayer, Marion; Harrer, Thomas; Kruse, Friedrich; Maas, Stefanie; Borst, Tobias; Heimke-Brinck, Ralph; Stog, Andreas; Knauer, Thomas; Rühl, Eva; Zeisberg, Victoria; Skornia, Adam; Bartsch, Alexander; Ströbel, Armin; Wytopil, Monika; Merkel, Caroline; Hofmann, Sophia; Schmidt, Katja G; Lakatos, Petra; Schottenhamml, Julia; Herrmann, Martin; Mardin, Christian; Rech, Jürgen
发表日期：2025
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Drug- and Cell-Type-Specific Effects of ROCK Inhibitors as a Potential Cause of Reticular Corneal Epithelial Edema

ROCK抑制剂的药物和细胞类型特异性效应可能是网状角膜上皮水肿的潜在原因

期刊:Cells
影响因子:5.2
doi:10.3390/cells14040258
Schlötzer-Schrehardt, Ursula; Gießl, Andreas; Zenkel, Matthias; Bartsch, Alexander; Okumura, Naoki; Koizumi, Noriko; Kinoshita, Shigeru; Tourtas, Theofilos; Kruse, Friedrich E
细胞生物学
ROCK
发表日期：2025
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Therapeutic Potential of Emricasan, a Pan-Caspase Inhibitor, in Reducing Cell Death and Extracellular Matrix Accumulation in Fuchs Endothelial Corneal Dystrophy

Emricasan（一种泛半胱天冬酶抑制剂）在减少 Fuchs 内皮角膜营养不良中的细胞死亡和细胞外基质积累方面的治疗潜力

期刊:Cells
影响因子:5.2
doi:10.3390/cells14070498
Fujimoto, Sohya; Endo, Mako; Tonomura, Shigehito; Tsuji, Fuuga; Haraguchi, Hirotaka; Hasegawa, Kanna; Numao, Taisuke; Izumi, Ayaka; Tourtas, Theofilos; Schlötzer-Schrehardt, Ursula; Kruse, Friedrich; Oyama, Yuki; Ikawa, Masahito; Jun, Albert S; Koizumi, Noriko; Okumura, Naoki
细胞生物学
发表日期：2025
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The TCF4 Gene Regulates Apoptosis of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy

TCF4基因调控Fuchs内皮角膜营养不良中角膜内皮细胞的凋亡

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.3.16
Nakagawa, Tatsuya; Honda, Tetsuro; Yuasa, Taichi; Nishiuchi, Go; Sato, Masakazu; Tokunaga, Ayumi; Nakahara, Makiko; Tourtas, Theofilos; Schlötzer-Schrehardt, Ursula; Kruse, Friedrich; Padmanabhan, Prema; Chatterjee, Amit; Sathe, Gajanan; Ghose, Vivek; Janakiraman, Narayanan; Blake, Derek J; Koizumi, Noriko; Elchuri, Sailaja; Okumura, Naoki
凋亡
表观遗传
Apoptosis
信号转导
内皮细胞
细胞生物学
发表日期：2025
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The PERK-p38 MAPK Axis Drives Endoplasmic Reticulum Stress-Induced Apoptosis in Fuchs Endothelial Corneal Dystrophy

PERK-p38 MAPK轴驱动Fuchs内皮角膜营养不良中内质网应激诱导的细胞凋亡

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.11.63
Onishi, Takako; Yuasa, Taichi; Ueda, Naoyuki; Miyadai, Keita; Tourtas, Theofilos; Schlötzer-Schrehardt, Ursula; Kruse, Friedrich; Koizumi, Noriko; Okumura, Naoki
凋亡
p38 MAPK
表观遗传
Apoptosis
内质网应激
MAPK/ERK
细胞生物学
PERK
发表日期：2025
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Protective Effects of Estradiol on Disease Progression in a Murine Model of Fuchs Endothelial Corneal Dystrophy

雌二醇对 Fuchs 内皮角膜营养不良小鼠模型疾病进展的保护作用

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.15.64
Oka, Itsuki; Fujimoto, Sohya; Fukui, Tomohiro; Mayumi, Kota; Tourtas, Theofilos; Schlötzer-Schrehardt, Ursula; Kruse, Friedrich; Jun, Albert S; Koizumi, Noriko; Okumura, Naoki
发表日期：2025
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Establishment of an Advanced In Vitro Model for Pseudoexfoliation Syndrome and Glaucoma

建立假性剥脱综合征和青光眼的高级体外模型

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.12.61
Pulasani, Sai; Zenkel, Matthias; Lämmer, Robert; Jünemann, Anselm; Gießl, Andreas; Korn, Klaus; Kruse, Friedrich E; Pasutto, Francesca; Schlötzer-Schrehardt, Ursula
神经科学
青光眼
发表日期：2025
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Comprehensive analysis of splicing variants in corneal endothelial cells of patients with Fuchs endothelial corneal dystrophy

对 Fuchs 内皮角膜营养不良患者角膜内皮细胞剪接变异体的综合分析

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-92119-0
Yuasa, Taichi; Tokuda, Yuichi; Nakano, Masakazu; Tashiro, Kei; Tourtas, Theofilos; Schlötzer-Schrehardt, Ursula; Kruse, Friedrich; Koizumi, Noriko; Okumura, Naoki
细胞生物学
内皮细胞
发表日期：2025
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A feasibility of computational drug screening for Fuchs endothelial corneal dystrophy

利用计算机辅助药物筛选治疗 Fuchs 内皮角膜营养不良的可行性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-95003-z
Oka, Itsuki; Toyokawa, Yoshiaki; Imai, Kouta; Nakagawa, Tatsuya; Tourtas, Theofilos; Schlötzer-Schrehardt, Ursula; Kruse, Friedrich; Koizumi, Noriko; Okumura, Naoki
发表日期：2025
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