日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

PRMT1-mediated asymmetric dimethylation of arginine residue 602 in DDX1 promotes cholangiocarcinoma progression

PRMT1介导的DDX1中精氨酸残基602的不对称二甲基化促进胆管癌进展

期刊:Clinical and Molecular Hepatology
影响因子:16.9
doi:10.3350/cmh.2025.1252
Liu, Wenzheng; Liao, Yangwei; Kuai, Yiyang; Gao, Xin; Yan, Xingmin; Li, Jingjing; Chen, Junsheng; Su, Jukun; Zhou, Jingcong; Kong, Yizhu; Huang, Siqin; Zhang, Zhiwei; Peng, Feng; Wang, Bing; Chen, Yongjun
表观遗传
PRMT1
DDX1
胆管癌
肿瘤
肿瘤免疫
发表日期：2026
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KDM4A-driven SMAD5/TGFβ axis activation as a therapeutic target in cholangiocarcinoma: mechanistic insights and translational implications

KDM4A驱动的SMAD5/TGFβ轴激活作为胆管癌的治疗靶点：机制解析及转化意义

期刊:Cell and Bioscience
影响因子:6.2
doi:10.1186/s13578-025-01472-0
Wang, Qi; Kuai, Yiyang; Xiong, Fei; Wang, Da; Wu, Guanhua; Liu, Wenzheng; Chen, Junsheng; Wang, Bing; Chen, Yongjun
肿瘤
肿瘤免疫
胆管癌
KDM4A
TGFβ
发表日期：2025
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PPM1G Inhibits Epithelial-Mesenchymal Transition in Cholangiocarcinoma by Catalyzing TET1 Dephosphorylation for Destabilization to Impair Its Targeted Demethylation of the CLDN3 Promoter.

PPM1G 通过催化 TET1 去磷酸化使其不稳定，从而抑制胆管癌的上皮-间质转化，进而损害其对 CLDN3 启动子的靶向去甲基化

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202407323
Liu Wenzheng, Kuai Yiyang, Wang Da, Chen Junsheng, Xiong Fei, Wu Guanhua, Wang Qi, Huang Wenhua, Qi Yongqiang, Wang Bing, Chen Yongjun
表观遗传
DNA甲基化
磷酸化
发表日期：2024
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Correction: STUB1-mediated K63-linked ubiquitination of UHRF1 promotes the progression of cholangiocarcinoma by maintaining DNA hypermethylation of PLA2G2A

更正：STUB1介导的UHRF1 K63连接泛素化通过维持PLA2G2A的DNA高甲基化促进胆管癌的进展

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-024-03198-2
Chen, Junsheng; Wang, Da; Wu, Guanhua; Xiong, Fei; Liu, Wenzheng; Wang, Qi; Kuai, Yiyang; Huang, Wenhua; Qi, Yongqiang; Wang, Bing; Chen, Yongjun
肿瘤
表观遗传
肿瘤免疫
泛素化
PLA2G2A
UHRF1
胆管癌
发表日期：2024
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Pathological complete response following neoadjuvant chemotherapy with PD-1 inhibitor for locally advanced pancreatic cancer: case report

局部晚期胰腺癌患者接受PD-1抑制剂新辅助化疗后达到病理完全缓解：病例报告

期刊:Journal of Gastrointestinal Oncology
影响因子:2
doi:10.21037/jgo-24-549
Chen, Junsheng; Wang, Da; Xiong, Fei; Wu, Guanhua; Liu, Wenzheng; Wang, Qi; Kuai, Yiyang; Peng, Feng; Chen, Yongjun
胰腺癌
肿瘤
肿瘤免疫
PD-1
发表日期：2024
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