日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Sensing of DNA double-strand breaks by the NHEJ system stabilizes RORγt transcriptional activity and shapes Th17 pathogenicity in autoimmunity

NHEJ系统对DNA双链断裂的感知可稳定RORγt转录活性，并影响Th17在自身免疫中的致病性。

期刊:Cell Research
影响因子:25.9
doi:10.1038/s41422-025-01204-6
Chen, Guan-Yu; Zhu, Wen-Jie; Li, Zhuang; Hu, Yun-Wei; Luo, Xiao-Shuang; Mai, Zhi-Qing; Pan, Yuan; Shi, Yu-Xun; Li, Zuo-Yi; Huang, Jun; Yuan, Pei-Dong; Xiao, Zhi-Qiang; Chen, Qian; Xie, Yan-Yan; Huang, Hai-Xiang; Chen, Yu-Xi; Lu, Yao; Wang, Min-Zhen; Xia, Yi-Wen; Chen, Xiao-Qing; Kuang, Dong-Ming; Liang, Dan
RORγt
免疫/内分泌
发表日期：2026
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Detection of plasma EV-associated TRAIL by nanoscale flow cytometry for liver metastasis prediction in PDAC.

利用纳米级流式细胞术检测血浆 EV 相关 TRAIL 以预测 PDAC 肝转移。

期刊:Adv Biotechnol (Singap)
影响因子:
doi:10.1007/s44307-026-00102-1
Huang Chun-Xiang, Jian Jia-Hong, Hao Jun-Sheng, Zhou Zi-Wen, Li Zhuo-Qun, Kuang Dong-Ming, Wu Cai-Yuan
细胞生物学
TRAIL
发表日期：2026
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Intracellular IL1α in Peritumoral Monocytes Induces IL8 Production and Inhibits Mitophagy to Promote Stemness and Metastasis of Hepatocellular Carcinoma

肿瘤周围单核细胞内的IL-1α诱导IL-8产生并抑制线粒体自噬，从而促进肝细胞癌的干性和转移。

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-24-3355
Ruan, Yong-Hao; Ning, Wan-Ru; Huang, Ai-Qi; Jiang, Da; Zhu, Bai-Xi; Liu, Xing-Chen; Gong, Jiang-Ling; Huang, Kun; Kuang, Dong-Ming; Wu, Yan; Zheng, Limin
肿瘤
肿瘤免疫
IL-8
线粒体
单核细胞
IL-1α
细胞生物学
自噬
发表日期：2025
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Tribbles Pseudokinase 3 Converts Sorafenib Therapy to Neutrophil-Mediated Lung Metastasis in Hepatocellular Carcinoma

Tribbles 假激酶 3 将索拉非尼治疗转化为肝细胞癌中性粒细胞介导的肺转移

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202413682
Wang, Xu-Yan; Liao, Yuan; Wang, Rui-Qi; Lu, Yi-Tong; Wang, Ying-Zhe; Xin, Yu-Qi; Kuang, Dong-Ming; Lao, Xiang-Ming; Xu, Junying; Zhou, Zhi-Ling; Hu, Kunhua
肿瘤
中性粒细胞
肿瘤免疫
信号转导
粒细胞
细胞生物学
发表日期：2025
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Correction: c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses

更正：c-Myc驱动的糖酵解使功能性调节性B细胞极化，从而触发致病性炎症反应。

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-024-01783-7
Wang, Xu-Yan; Wei, Yuan; Hu, Bo; Liao, Yuan; Wang, Xiaodong; Wan, Wen-Hua; Huang, Chun-Xiang; Mahabati, Mahepali; Liu, Zheng-Yu; Qu, Jing-Rui; Chen, Xiao-Dan; Chen, Dong-Ping; Kuang, Dong-Ming; Wang, Xue-Hao; Chen, Yun
B细胞
细胞生物学
免疫/内分泌
炎症
炎症/感染
发表日期：2024
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miRNome targeting NF-κB signaling orchestrates macrophage-triggered cancer metastasis and recurrence.

miRNome靶向NF-κB信号通路调控巨噬细胞触发的癌症转移和复发

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2024.02.009
Chen Dong-Ping, Wang Jun-Cheng, Liu Zheng-Yu, Li Pei-Lin, Chan Ka-Wo, Wu Xiang-Ning, Yao Wu-De-Xin, Yao Tingting, Kuang Dong-Ming, Wei Yuan
细胞生物学
NF-κB
发表日期：2024
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Cross-talk between Myeloid and B Cells Shapes the Distinct Microenvironments of Primary and Secondary Liver Cancer

髓系细胞和 B 细胞之间的相互作用形成了原发性和继发性肝癌的独特微环境

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-23-0193
Zhihang Chen #, Guopei Zhang #, Xiaoxue Ren #, Zhijia Yao #, Qian Zhou, Xuxin Ren, Shuling Chen, Lixia Xu, Kaiyu Sun, Qianwen Zeng, Ming Kuang, Dong-Ming Kuang, Sui Peng
免疫
细胞生物学
肝癌
B细胞
发表日期：2023
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c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses

c-Myc驱动的糖酵解使功能性调节性B细胞极化，从而触发致病性炎症反应。

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-022-00948-6
Wang, Xu-Yan; Wei, Yuan; Hu, Bo; Liao, Yuan; Wang, Xiaodong; Wan, Wen-Hua; Huang, Chun-Xiang; Mahabati, Mahepali; Liu, Zheng-Yu; Qu, Jing-Rui; Chen, Xiao-Dan; Chen, Dong-Ping; Kuang, Dong-Ming; Wang, Xue-Hao; Chen, Yun
B细胞
炎症
炎症/感染
细胞生物学
免疫/内分泌
发表日期：2022
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Immune landscape and therapeutic strategies: new insights into PD-L1 in tumors

免疫图谱与治疗策略：肿瘤中PD-L1的新见解

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-020-03637-1
Wei, Yuan; Xiao, Xiao; Lao, Xiang-Ming; Zheng, Limin; Kuang, Dong-Ming
PD-L1
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2021
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BTLA identifies dysfunctional PD-1-expressing CD4(+) T cells in human hepatocellular carcinoma

BTLA可识别人类肝细胞癌中功能异常的PD-1表达CD4(+) T细胞

期刊:Oncoimmunology
影响因子:6.3
doi:10.1080/2162402X.2016.1254855
Zhao, Qiyi; Huang, Zhan-Lian; He, Min; Gao, Zhiliang; Kuang, Dong-Ming
肿瘤
T细胞
肿瘤免疫
PD-1
T细胞
细胞生物学
CD4
免疫/内分泌
发表日期：2016
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