Dexmedetomidine alleviates sepsis-associated acute kidney injury by inhibiting renal tubular ferroptosis via JNK/MAPK-LCN2 pathway.
右美托咪定通过 JNK/MAPK-LCN2 通路抑制肾小管铁死亡，从而减轻脓毒症相关的急性肾损伤。
期刊:European Journal of Medical Research
影响因子:3.4
doi:10.1186/s40001-026-03953-5
Liu Boyang, Ao Shengxiang, Luo Li, Qiao Lin, Kuang Tianyin, Xiao Hongyan, Zhou Jing, Yin Shuangqin, Liang Huaping, Li Fen, Dai Weihong, Zhu Junyu
肾损伤
信号转导
JNK
Mapk
LCN2
MAPK/ERK
铁死亡
