日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A STAT1-Knockout Mouse Model for Chapare Virus Infection and Pathogenesis

STAT1基因敲除小鼠模型在查帕雷病毒感染和致病机制研究中的应用

Monticelli, Stephanie R; Kuehne, Ana I; Batchelor, Thomas G; Richardson, Joshua B; Lapoint, Zebulon; Williams, Jennifer L; Coyne, Susan R; Raymond, Jo Lynne W; Zeng, Xiankun; Stefan, Christopher P; Koehler, Jeffrey W; Kugelman, Jeffrey R; Herbert, Andrew S

Engineering and structures of Crimean-Congo hemorrhagic fever virus glycoprotein complexes.

克里米亚-刚果出血热病毒糖蛋白复合物的工程和结构

McFadden Elizabeth, Monticelli Stephanie R, Wang Albert, Ramamohan Ajit R, Batchelor Thomas G, Kuehne Ana I, Bakken Russell R, Tse Alexandra L, Chandran Kartik, Herbert Andrew S, McLellan Jason S

Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread

针对克里米亚-刚果出血热病毒GP38的抗体可限制血管渗漏和病毒传播。

Pahmeier, Felix; Monticelli, Stephanie R; Feng, Xinyi; Hjorth, Christy K; Wang, Albert; Kuehne, Ana I; Bakken, Russell R; Batchelor, Thomas G; Lee, Saeyoung E; Middlecamp, Marissa; Stuart, Lauren; Duarte-Neto, Amaro N; Abelson, Dafna M; McLellan, Jason S; Biering, Scott B; Herbert, Andrew S; Chandran, Kartik; Harris, Eva

Avidity and variable domain spacing strongly influence the therapeutic potency of bispecific antibodies against Crimean-Congo hemorrhagic fever virus

亲和力和可变区间距对针对克里米亚-刚果出血热病毒的双特异性抗体的治疗效力有显著影响。

Wang, Albert; Monticelli, Stephanie R; Wirchnianski, Ariel S; Abelson, Dafna M; Kuehne, Ana I; Bakken, Russell R; Middlecamp, Marissa; Weingart, Michael; Vergnolle, Olivia; Bornholdt, Zachary A; Moyer, Crystal L; Berrigan, Jacob L; West, Brandyn R; Fels, J Maximilian; Zeitlin, Larry; Herbert, Andrew S; Chandran, Kartik; Bikash, Chowdhury Raihan; Lai, Jonathan R

Characterization of a STAT-1 Knockout Mouse Model for Machupo Virus Infection and Pathogenesis

STAT-1基因敲除小鼠模型在马丘波病毒感染和致病性方面的特征分析

Monticelli, Stephanie R; Kuehne, Ana I; Bakken, Russell R; Coyne, Susan R; Lewis, Kenise D; Raymond, Jo Lynne W; Zeng, Xiankun; Richardson, Joshua B; Lapoint, Zebulon; Williams, Jennifer L; Stefan, Christopher P; Kugelman, Jeffrey R; Koehler, Jeffrey W; Herbert, Andrew S

Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19

预防性使用单克隆抗体Adintrevimab可保护仓鼠和非人灵长类动物免受SARS-CoV-2感染,以预防COVID-19。

Zumbrun, Elizabeth E; Kaku, Chengzi I; Dillinger, Lukas; Zak, Samantha E; Kuehne, Ana I; Bakken, Russel R; Koehler, Jeffrey W; Delp, Korey L; Stefan, Christopher P; Kumar, Raina; Kugelman, Jeffrey R; Moreau, Alicia M; Zeng, Xiankun; Dye, John M; Herbert, Andrew S; Narayan, Kristin; Walker, Laura M

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans

SARS-CoV-2单克隆抗体组合AZD7442在非人灵长类动物中具有保护作用,并且在人体内具有较长的半衰期。

Loo, Yueh-Ming; McTamney, Patrick M; Arends, Rosalinda H; Abram, Michael E; Aksyuk, Anastasia A; Diallo, Seme; Flores, Daniel J; Kelly, Elizabeth J; Ren, Kuishu; Roque, Richard; Rosenthal, Kim; Streicher, Katie; Tuffy, Kevin M; Bond, Nicholas J; Cornwell, Owen; Bouquet, Jerome; Cheng, Lily I; Dunyak, James; Huang, Yue; Rosenbaum, Anton I; Pilla Reddy, Venkatesh; Andersen, Hanne; Carnahan, Robert H; Crowe, James E Jr; Kuehne, Ana I; Herbert, Andrew S; Dye, John M; Bright, Helen; Kallewaard, Nicole L; Pangalos, Menelas N; Esser, Mark T

1143. Prophylactic and Therapeutic Activity of AZD7442 (Tixagevimab/Cilgavimab) in SARS-CoV-2 Hamster Challenge Models

1143. AZD7442(Tixagevimab/Cilgavimab)在SARS-CoV-2仓鼠感染模型中的预防和治疗活性

Evans, M J; Keeling, J W; Loo, Yueh-Ming; Herbert, Andrew S; Kuehne, Ana I; McTamney, Patrick M; Roque, Richard; Moreau, Alicia M; Bakken, Russell; Stefan, Christopher P; Koehler, Jeffrey W; Delp, Korey L; Coyne, Susan R; Kane, Christopher D; Dye, John M; Cai, Yingyun; Esser, Mark T

Development of an antibody cocktail for treatment of Sudan virus infection

开发用于治疗苏丹病毒感染的抗体混合物

Herbert, Andrew S; Froude, Jeffery W; Ortiz, Ramon A; Kuehne, Ana I; Dorosky, Danielle E; Bakken, Russell R; Zak, Samantha E; Josleyn, Nicole M; Musiychuk, Konstantin; Jones, R Mark; Green, Brian; Streatfield, Stephen J; Wec, Anna Z; Bohorova, Natasha; Bohorov, Ognian; Kim, Do H; Pauly, Michael H; Velasco, Jesus; Whaley, Kevin J; Stonier, Spencer W; Bornholdt, Zachary A; Chandran, Kartik; Zeitlin, Larry; Sampey, Darryl; Yusibov, Vidadi; Dye, John M

Multiple viral proteins and immune response pathways act to generate robust long-term immunity in Sudan virus survivors

多种病毒蛋白和免疫反应通路共同作用,使苏丹病毒幸存者产生强大的长期免疫力。

Sobarzo, Ariel; Stonier, Spencer W; Radinsky, Olga; Gelkop, Sigal; Kuehne, Ana I; Edri, Avishay; Herbert, Andrew S; Fedida-Metula, Shlomit; Lutwama, Julius Julian; Yavelsky, Victoria; Davis, Claytus; Porgador, Angel; Dye, John M; Lobel, Leslie