Dynamic compaction of human mesenchymal stem/precursor cells into spheres self-activates caspase-dependent IL1 signaling to enhance secretion of modulators of inflammation and immunity (PGE2, TSG6, and STC1).

人类间充质干细胞/前体细胞动态压缩成球体，可自我激活 caspase 依赖性 IL1 信号传导，从而增强炎症和免疫调节因子（PGE2、TSG6 和 STC1）的分泌