日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phase I First-in-Human Dose Escalation Study of the oral SF3B1 modulator H3B-8800 in myeloid neoplasms

口服SF3B1调节剂H3B-8800治疗髓系肿瘤的I期首次人体剂量递增研究

Steensma, David P; Wermke, Martin; Klimek, Virginia M; Greenberg, Peter L; Font, Patricia; Komrokji, Rami S; Yang, Jay; Brunner, Andrew M; Carraway, Hetty E; Ades, Lionel; Al-Kali, Aref; Alonso-Dominguez, Juan M; Alfonso-Piérola, Ana; Coombs, Catherine C; Deeg, H Joachim; Flinn, Ian; Foran, James M; Garcia-Manero, Guillermo; Maris, Michael B; McMasters, Malgorzata; Micol, Jean-Baptiste; De Oteyza, Jaime Perez; Thol, Felicitas; Wang, Eunice S; Watts, Justin M; Taylor, Justin; Stone, Richard; Gourineni, Vikram; Marino, Alyssa J; Yao, Huilan; Destenaves, Benoit; Yuan, Xiaobin; Yu, Kun; Dar, Sara; Ohanjanian, Lernik; Kuida, Keisuke; Xiao, Jianjun; Scholz, Catherine; Gualberto, Antonio; Platzbecker, Uwe

Opportunities and Challenges in Implementation of Multiparameter Single Cell Analysis Platforms for Clinical Translation

多参数单细胞分析平台在临床转化应用中的机遇与挑战

Keating, Susan M; Taylor, D Lansing; Plant, Anne L; Litwack, E David; Kuhn, Peter; Greenspan, Emily J; Hartshorn, Christopher M; Sigman, Caroline C; Kelloff, Gary J; Chang, David D; Friberg, Gregory; Lee, Jerry S H; Kuida, Keisuke

Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure

利用新型转基因小鼠进行活体细胞凋亡成像,突显了其在神经管闭合中的作用。

Yamaguchi, Yoshifumi; Shinotsuka, Naomi; Nonomura, Keiko; Takemoto, Kiwamu; Kuida, Keisuke; Yosida, Hiroki; Miura, Masayuki

Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury.

抑制自噬可防止缺氧缺血性损伤后海马锥体神经元死亡

Koike Masato, Shibata Masahiro, Tadakoshi Masao, Gotoh Kunihito, Komatsu Masaaki, Waguri Satoshi, Kawahara Nobutaka, Kuida Keisuke, Nagata Shigekazu, Kominami Eiki, Tanaka Keiji, Uchiyama Yasuo

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

半胱天冬酶3和7:线粒体凋亡事件的关键介质

Lakhani, Saquib A; Masud, Ali; Kuida, Keisuke; Porter, George A Jr; Booth, Carmen J; Mehal, Wajahat Z; Inayat, Irteza; Flavell, Richard A

Transforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells

转化生长因子β依赖的Smad、Bim和caspase-9的顺序激活介导胃上皮细胞的生理性凋亡。

Ohgushi, Masatoshi; Kuroki, Shunsuke; Fukamachi, Hiroshi; O'Reilly, Lorraine A; Kuida, Keisuke; Strasser, Andreas; Yonehara, Shin

Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation

体内脑缺血和体外氧糖剥夺后,caspase-3缺陷小鼠的caspase激活和神经保护作用

Le, Dean A; Wu, Yongqin; Huang, Zhihong; Matsushita, Kohji; Plesnila, Nikolaus; Augustinack, Jean C; Hyman, Bradley T; Yuan, Junying; Kuida, Keisuke; Flavell, Richard A; Moskowitz, Michael A