日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Endoglucanase 2 (Eng2), a shared immunodominant antigen in dimorphic fungi that elicits immunity during infection

内切葡聚糖酶 2 (Eng2) 是双相型真菌中一种共有的免疫优势抗原,可在感染过程中诱导免疫反应。

Uju J Okaa ,Cleison Ledesma Taira ,Lucas Dos Santos Dias ,Hannah Dobson ,Gregory C Kujoth ,Althea Campuzano ,E Jane Homan ,George R Thompson ,Chiung-Yu Hung ,George S Deepe Jr ,Marcel Wüthrich ,Bruce S Klein

Endoglucanase-2 (Eng2), a conserved immunodominant antigen in dimorphic fungi that elicits immunity and resistance during infection

内切葡聚糖酶-2 (Eng2) 是双相型真菌中一种保守的免疫优势抗原,可在感染过程中诱导免疫和抵抗力。

Okaa, Uju Joy; Taira, Cleison Ledesma; Dos Santos Dias, Lucas; Dobson, Hannah; Kujoth, Gregory; Campuzano, Althea; Homan, Jane; Thompson, George R; Hung, ChiungYu; Deepe, George S; Wüthrich, Marcel; Klein, Bruce S

Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity

芽生菌内切葡聚糖酶-2在抗真菌和抗病毒免疫中的佐剂作用的结构基础

Lucas Dos Santos Dias ,Hannah E Dobson ,Brock Kingstad Bakke ,Gregory C Kujoth ,Junfeng Huang ,Elaine M Kohn ,Cleison Ledesma Taira ,Huafeng Wang ,Nitin T Supekar ,J Scott Fites ,Daisy Gates ,Christina L Gomez ,Charles A Specht ,Stuart M Levitz ,Parastoo Azadi ,Lingjun Li ,Marulasiddappa Suresh ,Bruce S Klein ,Marcel Wüthrich

Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation

细胞受体 TRPV4 作为损伤传感器驱动肺部过敏性炎症

Darin L Wiesner ,Richard M Merkhofer ,Carole Ober ,Gregory C Kujoth ,Mengyao Niu ,Nancy P Keller ,James E Gern ,Rebecca A Brockman-Schneider ,Michael D Evans ,Daniel J Jackson ,Thomas Warner ,Nizar N Jarjour ,Stephane J Esnault ,Michael B Feldman ,Matthew Freeman ,Hongmei Mou ,Jatin M Vyas ,Bruce S Klein

Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance

抗原发现揭示了驻留记忆细胞和迁移细胞在抗真菌耐药性中的作用

Hannah E Dobson ,Lucas Dos Santos Dias ,Elaine M Kohn ,Scott Fites ,Darin L Wiesner ,Thamotharampillai Dileepan ,Gregory C Kujoth ,Ambily Abraham ,Gary R Ostroff ,Bruce S Klein ,Marcel Wüthrich

Prematurely aging mitochondrial DNA mutator mice display subchondral osteopenia and chondrocyte hypertrophy without further osteoarthritis features

过早衰老的线粒体 DNA 突变小鼠表现出软骨下骨质减少和软骨细胞肥大,但没有进一步的骨关节炎特征

Jeroen Geurts #, Sonia Nasi #, Pascal Distel, Magdalena Müller-Gerbl, Tomas A Prolla, Gregory C Kujoth, Ulrich A Walker, Thomas Hügle

Establishment of Quantitative PCR Assays for Active Long Interspersed Nuclear Element-1 Subfamilies in Mice and Applications to the Analysis of Aging-Associated Retrotransposition

建立小鼠活性长散在核元件-1亚家族的定量PCR检测方法及其在衰老相关逆转录转座分析中的应用

Kuroki, Ryota; Murata, Yui; Fuke, Satoshi; Nakachi, Yutaka; Nakashima, Jun; Kujoth, Gregory C; Prolla, Tomas A; Bundo, Miki; Kato, Tadafumi; Iwamoto, Kazuya

Gene Editing in Dimorphic Fungi Using CRISPR/Cas9.

利用 CRISPR/Cas9 对二型真菌进行基因编辑

Kujoth Gregory C, Sullivan Thomas D, Klein Bruce S

CRISPR/Cas9-Mediated Gene Disruption Reveals the Importance of Zinc Metabolism for Fitness of the Dimorphic Fungal Pathogen Blastomyces dermatitidis

CRISPR/Cas9介导的基因敲除揭示了锌代谢对双相型真菌病原体皮炎芽生菌适应性的重要性

Kujoth, Gregory C; Sullivan, Thomas D; Merkhofer, Richard; Lee, Taek-Jin; Wang, Huafeng; Brandhorst, Tristan; Wüthrich, Marcel; Klein, Bruce S

Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice

热量限制对 POLG 线粒体突变小鼠寿命和健康的影响

Shinichi Someya, Gregory C Kujoth, Mi-Jung Kim, Timothy A Hacker, Marc Vermulst, Richard Weindruch, Tomas A Prolla