7D, a small molecule inhibits dengue infection by increasing interferons and neutralizing-antibodies via CXCL4:CXCR3:p38:IRF3 and Sirt1:STAT3 axes respectively
7D是一种小分子,它分别通过CXCL4:CXCR3:p38:IRF3和Sirt1:STAT3通路增加干扰素和中和抗体,从而抑制登革热感染。
期刊:EMBO Molecular Medicine
影响因子:9
doi:10.1038/s44321-024-00137-8
Kishan Kumar Gaur #,Tejeswara Rao Asuru #,Mitul Srivastava,Nitu Singh,Nikil Purushotham,Boja Poojary,Bhabatosh Das,Sankar Bhattacharyya #,Shailendra Asthana #,Prasenjit Guchhait #
登革热
信号转导
CXCL4
CXCR3
IRF3
STAT3
SirT1