日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Environmental pH controls antimicrobial production by human probiotic Streptococcus salivarius

环境pH值控制着人类益生菌唾液链球菌的抗菌物质产生。

Nguyen, Dieu Linh; Saha, Subhasree; Thacharodi, Aswin; Singh, Bharat Bhushan; Mitra, Sonali; Do, Hackwon; Kumaraswami, Muthiah

A zinc-free alternative ribosomal protein RpsN.2 confers survival advantage to group A streptococcus during Zn scarcity

一种不含锌的替代核糖体蛋白RpsN.2在锌缺乏期间赋予A群链球菌生存优势

Saha, Subhasree; Thacharodi, Aswin; Nguyen, Dieu Linh; Makthal, Nishanth; Bernard, Charles; Kumaraswami, Muthiah

Description of the draft genome sequence of Streptococcus salivarius eK12, a derivative of the probiotic strain Streptococcus salivarius K12 with a modified plasmid

对链球菌唾液菌株 eK12 的基因组序列草图进行了描述,该菌株是益生菌菌株链球菌唾液菌株 K12 的衍生菌株,带有修饰的质粒。

Di Pierro, Francesco; Thacharodi, Aswin; Kumaraswami, Muthiah; Bertuccioli, Alexander; Tanda, Maria Laura; Zerbinati, Nicola

Engineered probiotic overcomes pathogen defences using signal interference and antibiotic production to treat infection in mice

基因工程益生菌利用信号干扰和抗生素产生克服病原体的防御机制,从而治疗小鼠感染。

Do, Hackwon; Li, Zhong-Rui; Tripathi, Praveen Kumar; Mitra, Sonali; Guerra, Stephanie; Dash, Ananya; Weerasekera, Dulanthi; Makthal, Nishanth; Shams, Syed; Aggarwal, Shifu; Singh, Bharat Bhushan; Gu, Di; Du, Yongle; Olsen, Randall J; LaRock, Christopher; Zhang, Wenjun; Kumaraswami, Muthiah

The leaderless communication peptide (LCP) class of quorum-sensing peptides is broadly distributed among Firmicutes

无领导通讯肽(LCP)类群体感应肽广泛分布于厚壁菌门中。

Aggarwal, Shifu; Huang, Elaine; Do, Hackwon; Makthal, Nishanth; Li, Yanyan; Bapteste, Eric; Lopez, Philippe; Bernard, Charles; Kumaraswami, Muthiah

Managing Manganese: The Role of Manganese Homeostasis in Streptococcal Pathogenesis

锰的管理:锰稳态在链球菌致病机制中的作用

Aggarwal, Shifu; Kumaraswami, Muthiah

Group A Streptococcus AdcR Regulon Participates in Bacterial Defense against Host-Mediated Zinc Sequestration and Contributes to Virulence

A组链球菌AdcR调控子参与细菌防御宿主介导的锌螯合作用,并有助于其毒力增强。

Makthal, Nishanth; Do, Hackwon; Wendel, Brian M; Olsen, Randall J; Helmann, John D; Musser, James M; Kumaraswami, Muthiah

Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcus

毒力传感器激酶 CovS 的磷酸酶活性对 A 群链球菌的致病性至关重要

Horstmann, Nicola; Tran, Chau Nguyen; Brumlow, Chelcy; DebRoy, Sruti; Yao, Hui; Nogueras Gonzalez, Graciela; Makthal, Nishanth; Kumaraswami, Muthiah; Shelburne, Samuel A

Signaling by a Conserved Quorum Sensing Pathway Contributes to Growth Ex Vivo and Oropharyngeal Colonization of Human Pathogen Group A Streptococcus

保守的群体感应通路信号传导促进A群链球菌在体外的生长和口咽部的定植

Makthal, Nishanth; Do, Hackwon; VanderWal, Arica R; Olsen, Randall J; Musser, James M; Kumaraswami, Muthiah

Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen

一种无前导序列的分泌型肽信号分子能够改变整体基因表达,并增强人类致病菌的毒力。

Do, Hackwon; Makthal, Nishanth; VanderWal, Arica R; Rettel, Mandy; Savitski, Mikhail M; Peschek, Nikolai; Papenfort, Kai; Olsen, Randall J; Musser, James M; Kumaraswami, Muthiah