日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Fluorescence Characterization of Extracellular Vesicles Using Single-Molecule Confocal Microscopy

利用单分子共聚焦显微镜对细胞外囊泡进行荧光表征

Zhao, Tianxiao; Pelegrina-Hidalgo, Noelia; Edwards, Daniel C; Bąk, Krzysztof M; Karmakar, Utsa; Fernando, Anuruddika J; Vendrell, Marc; Rossi, Adriano G; Cockroft, Scott L; Kunath, Tilo; Saleeb, Rebecca S; Horrocks, Mathew H

Investigating the ageing-Parkinson's disease nexus: standardisation of in vitro models and techniques by the PD-AGE network

探索衰老与帕金森病之间的联系:PD-AGE网络对体外模型和技术的标准化

Bury, Alexander G; Olejnik, Alicja; Tocco, Chiara; Saurat, Nathalie; Stephen, Elezabeth; Hockemeyer, Dirk; Schwamborn, Jens C; Studer, Lorenz; Mastroberardino, Pier Giorgio; Bolognin, Silvia; Kunath, Tilo; Korolchuk, Viktor I; Drouin-Ouellet, Janelle; Mortiboys, Heather

A high-fidelity microfluidic platform reveals retrograde propagation as the main mechanism of α-Synuclein spread in human neurons.

高保真微流控平台揭示了逆行传播是α-突触核蛋白在人类神经元中扩散的主要机制

Vroman Rozan, de Lichtervelde Lorenzo, Singh Dolt Karamjit, Robertson Graham, Kriek Marco, Barbato Michela, Cholewa-Waclaw Justyna, Kunath Tilo, Downey Patrick, Zagnoni Michele

Glycine-to-aspartic acid mutation at codon 51 in Snca disrupts the synaptic localisation of α-synuclein and enhances its propensity for synucleinopathy.

Snca 基因第 51 位密码子上的甘氨酸突变为天冬氨酸,破坏了 α-突触核蛋白的突触定位,并增强了其发生突触核蛋白病的倾向

West Stephen, Natalwala Ammar, Singh Dolt Karamjit, Lamont Douglas J, McMillan Melanie, Luk Kelvin, Mashimo Tomoji, Kunath Tilo

Lipid-induced polymorphic amyloid fibril formation by α-synuclein

α-突触核蛋白诱导的脂质介导的多态性淀粉样蛋白原纤维形成

Singh, Bhanu P; Morris, Ryan J; Kunath, Tilo; MacPhee, Cait E; Horrocks, Mathew H

Determining the Location of the α-Synuclein Dimer Interface Using Native Top-Down Fragmentation and Isotope Depletion-Mass Spectrometry

利用天然自上而下碎片化和同位素损耗质谱法确定α-突触核蛋白二聚体界面位置

Jeacock, Kiani; Chappard, Alexandre; Gallagher, Kelly J; Mackay, C Logan; Kilgour, David P A; Horrocks, Mathew H; Kunath, Tilo; Clarke, David J

Author Correction: Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

作者更正:线粒体中α-突触核蛋白的病理结构转化会诱导神经元毒性

Choi, Minee L; Chappard, Alexandre; Singh, Bhanu P; Maclachlan, Catherine; Rodrigues, Margarida; Fedotova, Evgeniya I; Berezhnov, Alexey V; De, Suman; Peddie, Christopher J; Athauda, Dilan; Virdi, Gurvir S; Zhang, Weijia; Evans, James R; Wernick, Anna I; Zanjani, Zeinab Shadman; Angelova, Plamena R; Esteras, Noemi; Vinokurov, Andrey Y; Morris, Katie; Jeacock, Kiani; Tosatto, Laura; Little, Daniel; Gissen, Paul; Clarke, David J; Kunath, Tilo; Collinson, Lucy; Klenerman, David; Abramov, Andrey Y; Horrocks, Mathew H; Gandhi, Sonia

Erratum: CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity

勘误:CHIP依赖的肌动蛋白细胞骨架调控与神经元细胞膜完整性相关

Dias, Catarina; Nita, Erisa; Faktor, Jakub; Tynan, Ailish C; Hernychova, Lenka; Vojtesek, Borivoj; Nylandsted, Jesper; Hupp, Ted R; Kunath, Tilo; Ball, Kathryn L

Metabolomics of sebum reveals lipid dysregulation in Parkinson's disease

皮脂代谢组学揭示帕金森病中的脂质代谢紊乱

Sinclair, Eleanor; Trivedi, Drupad K; Sarkar, Depanjan; Walton-Doyle, Caitlin; Milne, Joy; Kunath, Tilo; Rijs, Anouk M; de Bie, Rob M A; Goodacre, Royston; Silverdale, Monty; Barran, Perdita

Cryopreservation of Human Midbrain Dopaminergic Neural Progenitor Cells Poised for Neuronal Differentiation

人类中脑多巴胺能神经祖细胞的冷冻保存及其向神经元分化的准备

Drummond, Nicola J; Singh Dolt, Karamjit; Canham, Maurice A; Kilbride, Peter; Morris, G John; Kunath, Tilo