日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells

通过过敏毒素 C5a 和 γδT 细胞连接小鼠脉络膜新生血管中的先天性和适应性免疫反应

Beth Coughlin, Gloriane Schnabolk, Kusumam Joseph, Himanshu Raikwar, Kannan Kunchithapautham, Krista Johnson, Kristi Moore, Yi Wang, Bärbel Rohrer

Local production of the alternative pathway component factor B is sufficient to promote laser-induced choroidal neovascularization

局部产生替代途径成分因子 B 足以促进激光诱导的脉络膜新生血管

Gloriane Schnabolk, Beth Coughlin, Kusumam Joseph, Kannan Kunchithapautham, Mausumi Bandyopadhyay, Elizabeth C O'Quinn, Tamara Nowling, Bärbel Rohrer

Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation

烟雾暴露通过氧化应激和补体激活引起视网膜色素上皮内质网应激和脂质积聚

Kannan Kunchithapautham, Carl Atkinson, Bärbel Rohrer

A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization

C57BL/6J 和 6N 亚系小鼠趋化因子/细胞因子表达及对激光诱导脉络膜新生血管的易感性比较分析

Schnabolk, Gloriane; Stauffer, Kimberly; O'Quinn, Elizabeth; Coughlin, Beth; Kunchithapautham, Kannan; Rohrer, Bärbel

Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner

氧化应激以天然抗体、凝集素途径和磷脂表位依赖的方式使视网膜色素上皮 (RPE) 细胞对补体介导的损伤敏感

Kusumam Joseph, Liudmila Kulik, Beth Coughlin, Kannan Kunchithapautham, Mausumi Bandyopadhyay, Steffen Thiel, Nicole M Thielens, V Michael Holers, Bärbel Rohrer

Differential effects of rapamycin on rods and cones during light-induced stress in albino mice

雷帕霉素对白化小鼠光应激期间视杆细胞和视锥细胞的不同影响

Kunchithapautham, Kannan; Coughlin, Beth; Lemasters, John J; Rohrer, Bärbel

Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers

亚溶解性膜攻击复合物 (MAC) 激活会改变视网膜色素上皮单层中受调节的而非组成性的血管内皮生长因子 (VEGF) 分泌

Kannan Kunchithapautham, Bärbel Rohrer

A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration

靶向替代补体途径的抑制剂可减少年龄相关性黄斑变性小鼠模型中的血管生成。

Rohrer, Bärbel; Long, Qin; Coughlin, Beth; Wilson, R Brooks; Huang, Yuxiang; Qiao, Fei; Tang, Peter H; Kunchithapautham, Kannan; Gilkeson, Gary S; Tomlinson, Stephen