日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PDK1 and YAP1/TEAD signaling drive acquired KRAS inhibitor resistance in KRAS-mutant non-small cell lung cancer

PDK1 和 YAP1/TEAD 信号通路驱动 KRAS 突变型非小细胞肺癌获得性 KRAS 抑制剂耐药性

Barua, Amrita; Kundu, Samrat T; Garza, Sofia G; Fradette, Jared J; Choudhary, Bhagya Shree; Peng, David H; Diao, Lixia; Wang, Jing; Gibbons, Don L

MBIP (MAP3K12 binding inhibitory protein) drives NSCLC metastasis by JNK-dependent activation of MMPs

MBIP(MAP3K12结合抑制蛋白)通过JNK依赖性激活MMPs驱动非小细胞肺癌转移

Ochieng, Joshua Kapere; Kundu, Samrat T; Bajaj, Rakhee; Leticia Rodriguez, B; Fradette, Jared J; Gibbons, Don L

ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism

ZEB1抑制通过IL17RD依赖性机制使KRAS突变型癌症对MEK抑制剂更加敏感。

Peng, David H; Kundu, Samrat T; Fradette, Jared J; Diao, Lixia; Tong, Pan; Byers, Lauren A; Wang, Jing; Canales, Jaime Rodriguez; Villalobos, Pamela A; Mino, Barbara; Yang, Yanan; Minelli, Rosalba; Peoples, Michael D; Bristow, Christopher A; Heffernan, Timothy P; Carugo, Alessandro; Wistuba, Ignacio I; Gibbons, Don L

Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis.

Plakophilin3 的缺失导致 PRL3 水平升高,促进 K8 去磷酸化,而 K8 去磷酸化是转化和转移所必需的

Khapare Nileema, Kundu Samrat T, Sehgal Lalit, Sawant Mugdha, Priya Rashmi, Gosavi Prajakta, Gupta Neha, Alam Hunain, Karkhanis Madhura, Naik Nishigandha, Vaidya Milind M, Dalal Sorab N

E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly

E-钙黏蛋白和桥粒蛋白募集桥粒蛋白3至细胞边界,启动桥粒组装。

Gosavi, Prajakta; Kundu, Samrat T; Khapare, Nileema; Sehgal, Lalit; Karkhanis, Mansi S; Dalal, Sorab N

Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells

角蛋白5和14在复层上皮细胞增殖和分化中的新功能

Alam, Hunain; Sehgal, Lalit; Kundu, Samrat T; Dalal, Sorab N; Vaidya, Milind M

Robust and specific inhibition of microRNAs in Caenorhabditis elegans

对秀丽隐杆线虫中microRNA的强效且特异性抑制

Kundu, Samrat T; Slack, Frank J