Kunkl相关文献与解析，生知库 | 链接生命科学的每一步

Colli, Camillo; De Filippis, Andrea; Galbo, Gabriele; Kunkl, Martina; Ivanova, Julia; Fornoni, Susan; Spatz, Joachim P; Rosanò, Laura; Moscatelli, Davide; Tuosto, Loretta; Mauri, Emanuele

发表日期：2026

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The GLP-1R agonist semaglutide reshapes pancreatic cancer associated fibroblasts reducing collagen proline hydroxylation and favoring T lymphocyte infiltration

GLP-1受体激动剂索玛鲁肽可重塑胰腺癌相关成纤维细胞，减少胶原蛋白脯氨酸羟基化，并促进T淋巴细胞浸润。

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:12.8

doi:10.1186/s13046-024-03263-w

Cencioni, Chiara; Malatesta, Silvia; Vigiano Benedetti, Virginia; Licursi, Valerio; Perfetto, Livia; Conte, Federica; Ranieri, Danilo; Bartolazzi, Armando; Kunkl, Martina; Tuosto, Loretta; Larghi, Alberto; Piro, Geny; Agostini, Antonio; Tortora, Giampaolo; Corbo, Vincenzo; Carbone, Carmine; Spallotta, Francesco

The extracellular matrix protein type I collagen and fibronectin are regulated by β-arrestin-1/endothelin axis in human ovarian fibroblasts

人卵巢成纤维细胞中的细胞外基质蛋白 I 型胶原蛋白和纤连蛋白受 β-arrestin-1/内皮素轴调控

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:11.4

doi:10.1186/s13046-025-03327-5

Ilenia Masi #, Flavia Ottavi #, Valentina Caprara, Danila Del Rio, Martina Kunkl, Francesca Spadaro, Valerio Licursi, Loretta Tuosto, Anna Bagnato, Laura Rosano'

An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction

轴性脊柱关节炎和银屑病关节炎患者体内一种免疫衰老的CD8+ T细胞亚群将自发性运动与端粒缩短和功能障碍联系起来

期刊:Arthritis & Rheumatology

影响因子:10.9

doi:10.1002/art.43109

Paldino, Giorgia; Tedeschi, Valentina; Proganò, Valentina; Salvati, Erica; Licursi, Valerio; Vertecchi, Eleonora; Bivolaru, Alexandru L; Molteni, Emanuele; Scrivo, Rossana; Congia, Mattia; Cauli, Alberto; Caccavale, Rosalba; Paroli, Marino; Kunkl, Martina; Tuosto, Loretta; Sorrentino, Rosa; Fiorillo, Maria Teresa

Targeting staphylococcal enterotoxin B binding to CD28 as a new strategy for dampening superantigen-mediated intestinal epithelial barrier dysfunctions

以葡萄球菌肠毒素 B 与 CD28 结合为靶点，作为抑制超抗原介导的肠上皮屏障功能障碍的新策略

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2024.1365074

Carola Amormino, Emanuela Russo, Valentina Tedeschi, Maria Teresa Fiorillo, Alessandro Paiardini, Francesco Spallotta, Laura Rosanò, Loretta Tuosto, Martina Kunkl

Bivalent binding of staphylococcal superantigens to the TCR and CD28 triggers inflammatory signals independently of antigen presenting cells

葡萄球菌超抗原与 TCR 和 CD28 的双价结合可独立于抗原呈递细胞触发炎症信号

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2023.1170821

Martina Kunkl, Carola Amormino, Francesco Spallotta, Silvana Caristi, Maria Teresa Fiorillo, Alessandro Paiardini, Raymond Kaempfer, Loretta Tuosto

SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity

SARS-CoV-2 刺突蛋白不具有内在超抗原样炎症活性

期刊:Cells

影响因子:5.1

doi:10.3390/cells11162526

Carola Amormino, Valentina Tedeschi, Giorgia Paldino, Stefano Arcieri, Maria Teresa Fiorillo, Alessandro Paiardini, Loretta Tuosto, Martina Kunkl

CD8(+) T Cell Senescence: Lights and Shadows in Viral Infections, Autoimmune Disorders and Cancer

CD8(+) T细胞衰老：病毒感染、自身免疫性疾病和癌症中的光明与阴影

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms23063374

Tedeschi, Valentina; Paldino, Giorgia; Kunkl, Martina; Paroli, Marino; Sorrentino, Rosa; Tuosto, Loretta; Fiorillo, Maria Teresa

Binding of Staphylococcal Enterotoxin B (SEB) to B7 Receptors Triggers TCR- and CD28-Mediated Inflammatory Signals in the Absence of MHC Class II Molecules

在没有 MHC II 类分子的情况下，葡萄球菌肠毒素 B (SEB) 与 B7 受体结合会触发 TCR 和 CD28 介导的炎症信号

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2021.723689

Martina Kunkl, Carola Amormino, Silvana Caristi, Valentina Tedeschi, Maria Teresa Fiorillo, Revital Levy, Andrey Popugailo, Raymond Kaempfer, Loretta Tuosto

信号转导

微生物学

Immunology/Inflammation

发表日期：2021

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CD28 Autonomous Signaling Orchestrates IL-22 Expression and IL-22-Regulated Epithelial Barrier Functions in Human T Lymphocytes

CD28 自主信号调节人类 T 淋巴细胞中的 IL-22 表达和 IL-22 调节的上皮屏障功能

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2020.590964

Martina Kunkl, Carola Amormino, Simone Frascolla, Manolo Sambucci, Marco De Bardi, Silvana Caristi, Stefano Arcieri, Luca Battistini, Loretta Tuosto

Metal-Coordinated His-Tag Functionalization of Polymeric Nanogels for Therapeutic Applications

金属配位组氨酸标签功能化修饰聚合物纳米凝胶用于治疗应用

The GLP-1R agonist semaglutide reshapes pancreatic cancer associated fibroblasts reducing collagen proline hydroxylation and favoring T lymphocyte infiltration

GLP-1受体激动剂索玛鲁肽可重塑胰腺癌相关成纤维细胞，减少胶原蛋白脯氨酸羟基化，并促进T淋巴细胞浸润。

The extracellular matrix protein type I collagen and fibronectin are regulated by β-arrestin-1/endothelin axis in human ovarian fibroblasts

人卵巢成纤维细胞中的细胞外基质蛋白 I 型胶原蛋白和纤连蛋白受 β-arrestin-1/内皮素轴调控

An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction

轴性脊柱关节炎和银屑病关节炎患者体内一种免疫衰老的CD8+ T细胞亚群将自发性运动与端粒缩短和功能障碍联系起来

Targeting staphylococcal enterotoxin B binding to CD28 as a new strategy for dampening superantigen-mediated intestinal epithelial barrier dysfunctions

以葡萄球菌肠毒素 B 与 CD28 结合为靶点，作为抑制超抗原介导的肠上皮屏障功能障碍的新策略

Bivalent binding of staphylococcal superantigens to the TCR and CD28 triggers inflammatory signals independently of antigen presenting cells

葡萄球菌超抗原与 TCR 和 CD28 的双价结合可独立于抗原呈递细胞触发炎症信号

SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity

SARS-CoV-2 刺突蛋白不具有内在超抗原样炎症活性

CD8(+) T Cell Senescence: Lights and Shadows in Viral Infections, Autoimmune Disorders and Cancer

CD8(+) T细胞衰老：病毒感染、自身免疫性疾病和癌症中的光明与阴影

Binding of Staphylococcal Enterotoxin B (SEB) to B7 Receptors Triggers TCR- and CD28-Mediated Inflammatory Signals in the Absence of MHC Class II Molecules

在没有 MHC II 类分子的情况下，葡萄球菌肠毒素 B (SEB) 与 B7 受体结合会触发 TCR 和 CD28 介导的炎症信号

CD28 Autonomous Signaling Orchestrates IL-22 Expression and IL-22-Regulated Epithelial Barrier Functions in Human T Lymphocytes

CD28 自主信号调节人类 T 淋巴细胞中的 IL-22 表达和 IL-22 调节的上皮屏障功能