日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Commentary: Adverse event profiles of PARP inhibitors: analysis of spontaneous reports submitted to FAERS

评论:PARP抑制剂不良事件概况:对提交至FAERS的自发报告的分析。

Schilder, Jeanne M; Golembesky, Amanda; Boyle, Tirza Areli Calderón; Ye, Gui Lan; Kuplast, Judi

PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

PARP7 负向调节癌细胞中的 I 型干扰素反应,其抑制可触发抗肿瘤免疫

Joseph M Gozgit, Melissa M Vasbinder, Ryan P Abo, Kaiko Kunii, Kristy G Kuplast-Barr, Bin Gui, Alvin Z Lu, Jennifer R Molina, Elena Minissale, Kerren K Swinger, Tim J Wigle, Danielle J Blackwell, Christina R Majer, Yue Ren, Mario Niepel, Zacharenia A Varsamis, Sunaina P Nayak, Ellen Bamberg, Jan-Run

Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models

通过抑制 EZH2 选择性杀死 SMARCA2 和 SMARCA4 缺陷型卵巢小细胞癌、高钙血症型细胞:体外和体内临床前模型

Elayne Chan-Penebre, Kelli Armstrong, Allison Drew, Alexandra R Grassian, Igor Feldman, Sarah K Knutson, Kristy Kuplast-Barr, Maria Roche, John Campbell, Peter Ho, Robert A Copeland, Richard Chesworth, Jesse J Smith, Heike Keilhack, Scott A Ribich

Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666

结构和性能引导设计在 PRMT5 工具化合物 EPZ015666 识别中的应用

Kenneth W Duncan, Nathalie Rioux, P Ann Boriack-Sjodin, Michael J Munchhof, Lawrence A Reiter, Christina R Majer, Lei Jin, L Danielle Johnston, Elayne Chan-Penebre, Kristy G Kuplast, Margaret Porter Scott, Roy M Pollock, Nigel J Waters, Jesse J Smith, Mikel P Moyer, Robert A Copeland, Richard Cheswo

T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures

型钙通道阻滞剂可减弱丘脑爆发放电并抑制失神发作

Elizabeth Tringham, Kim L Powell, Stuart M Cain, Kristy Kuplast, Janette Mezeyova, Manjula Weerapura, Cyrus Eduljee, Xinpo Jiang, Paula Smith, Jerrie-Lynn Morrison, Nigel C Jones, Emma Braine, Gil Rind, Molly Fee-Maki, David Parker, Hassan Pajouhesh, Manjeet Parmar, Terence J O'Brien, Terrance P Snu