Design, Synthesis, Dynamic Docking, Biochemical Characterization, and in Vivo Pharmacokinetics Studies of Novel Topoisomerase II Poisons with Promising Antiproliferative Activity
具有良好抗增殖活性的新型拓扑异构酶 II 毒物的设计、合成、动态对接、生化表征及体内药代动力学研究
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.9b01760
Jose M Arencibia, Nicoletta Brindani, Sebastian Franco-Ulloa, Michela Nigro, Jissy Akkarapattiakal Kuriappan, Giuliana Ottonello, Sine Mandrup Bertozzi, Maria Summa, Stefania Girotto, Rosalia Bertorelli, Andrea Armirotti, Marco De Vivo
