Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea Responsiveness
羟基脲对镰状细胞病患者成红细胞中γ-珠蛋白基因的激活因子和抑制因子的调节作用存在差异,且与羟基脲反应指数相关。
期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2017.175646
Zhu, Xingguo; Hu, Tianxiang; Ho, Meng Hsuan; Wang, Yongchao; Yu, Miao; Patel, Niren; Pi, Wenhu; Choi, Jeong-Hyeon; Xu, Hongyan; Ganapathy, Vadivel; Kutlar, Ferdane; Kutlar, Abdullah; Tuan, Dorothy