Kuttikrishnan相关文献与解析，生知库 | 链接生命科学的每一步

Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans

硼替佐米通过调节非黑色素瘤皮肤癌细胞和秀丽隐杆线虫中的 Skp2/p53 轴发挥其抗癌活性

doi:10.1038/s41420-024-01992-7

Kirti S Prabhu, Fareed Ahmad, Shilpa Kuttikrishnan, Rari Leo, Tayyiba Akbar Ali, Mahmoud Izadi, Jericha M Mateo, Majid Alam, Aamir Ahmad, Ammira S Al-Shabeeb Akil, Ajaz A Bhat, Joerg Buddenkotte, Ehsan Pourkarimi, Martin Steinhoff, Shahab Uddin3

Anticancer Potential and Molecular Targets of Pristimerin in Human Malignancies

普利司汀在人类恶性肿瘤中的抗癌潜力和分子靶点

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph17050578

Prabhu, Kirti S; Jessy, Serah; Kuttikrishnan, Shilpa; Mujeeb, Farina; Mariyam, Zahwa; Habeeba, Ummu; Ahmad, Nuha; Bhat, Ajaz A; Uddin, Shahab

Human

发表日期：2024

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Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer

基于网络药理学、分子模拟和结合自由能计算的新孢子素B研究揭示了癌症治疗的关键靶点。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2024.1352907

Khan, Abbas; Waheed, Yasir; Kuttikrishnan, Shilpa; Prabhu, Kirti S; El-Elimat, Tamam; Uddin, Shahab; Alali, Feras Q; Agouni, Abdelali

Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway

新骨肉瘤素B通过靶向AKT/SKP2信号通路诱导多发性骨髓瘤细胞凋亡

期刊:Cell Biology International

影响因子:3.3

doi:10.1002/cbin.12101

Shilpa Kuttikrishnan, Fareed Ahmad, Jericha M Mateo, Kirti S Prabhu, Tamam El-Elimat, Nicholas H Oberlies, Cedric J Pearce, Ammira S Alshabeeb Akil, Ajaz A Bhat, Feras Q Alali, Shahab Uddin

In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway

体外评价新骨肉瘤素B通过靶向FOXM1信号通路诱导皮肤T细胞淋巴瘤细胞凋亡

期刊:Journal of Dermatological Science

影响因子:3.8

doi:10.1016/j.jdermsci.2023.10.001

Shilpa Kuttikrishnan, Tariq Masoodi, Fareed Ahmad, Gulab Sher, Kirti S Prabhu, Jericha M Mateo, Joerg Buddenkotte, Tamam El-Elimat, Nicholas H Oberlies, Cedric J Pearce, Ajaz A Bhat, Feras Q Alali, Martin Steinhoff, Shahab Uddin2

Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway

古古甾酮通过靶向高迁移率族蛋白1（HMGB1）并经由Janus激酶/信号转导及转录激活因子通路诱导多发性骨髓瘤细胞凋亡

期刊:Cancers

影响因子:4.4

doi:10.3390/cancers14225621

Akhtar, Sabah; Zarif, Lubna; Kuttikrishnan, Shilpa; Prabhu, Kirti S; Patil, Kalyani; Nisar, Sabah; Abou-Saleh, Haissam; Merhi, Maysaloun; Dermime, Said; Bhat, Ajaz A; Uddin, Shahab

Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis

生物信息学分析揭示 FOXM1/BUB1B 信号通路是人类白血病细胞中新骨化素 B 的关键靶点：基于基因网络的微阵列分析

期刊:Frontiers in Oncology

影响因子:3.5

doi:10.3389/fonc.2022.929996

Shilpa Kuttikrishnan, Tariq Masoodi, Gulab Sher, Ajaz A Bhat, Kalyani Patil, Tamam El-Elimat, Nicholas H Oberlies, Cedric J Pearce, Mohmmad Haris, Aamir Ahmad, Feras Q Alali, Shahab Uddin

Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells

新骨肉瘤素 B 通过靶向白血病细胞中的 AKT/SKP2/MTH1 轴发挥抗癌作用

期刊:Biochemical and Biophysical Research Communications

影响因子:2.5

doi:10.1016/j.bbrc.2022.02.071

Shilpa Kuttikrishnan, Ajaz A Bhat, Jericha M Mateo, Fareed Ahmad, Feras Q Alali, Tamam El-Elimat, Nicholas H Oberlies, Cedric J Pearce, Shahab Uddin

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway

血根碱通过产生活性氧和抑制 JAK/STAT 通路介导非小细胞肺癌细胞凋亡

期刊:Biomedicine & Pharmacotherapy

影响因子:6.9

doi:10.1016/j.biopha.2021.112358

Kirti S Prabhu, Ajaz A Bhat, Kodappully S Siveen, Shilpa Kuttikrishnan, Syed Shadab Raza, Thesni Raheed, Anh Jochebeth, Abdul Q Khan, M Zafar Chawdhery, Mohammad Haris, Michal Kulinski, Said Dermime, Martin Steinhoff, Shahab Uddin

PI3 K/AKT/mTOR pathway and its role in breast cancer stem cells

PI3K/AKT/mTOR通路及其在乳腺癌干细胞中的作用

Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans

硼替佐米通过调节非黑色素瘤皮肤癌细胞和秀丽隐杆线虫中的 Skp2/p53 轴发挥其抗癌活性

Anticancer Potential and Molecular Targets of Pristimerin in Human Malignancies

普利司汀在人类恶性肿瘤中的抗癌潜力和分子靶点

Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer

基于网络药理学、分子模拟和结合自由能计算的新孢子素B研究揭示了癌症治疗的关键靶点。

Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway

新骨肉瘤素B通过靶向AKT/SKP2信号通路诱导多发性骨髓瘤细胞凋亡

In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway

体外评价新骨肉瘤素B通过靶向FOXM1信号通路诱导皮肤T细胞淋巴瘤细胞凋亡

Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway

古古甾酮通过靶向高迁移率族蛋白1（HMGB1）并经由Janus激酶/信号转导及转录激活因子通路诱导多发性骨髓瘤细胞凋亡

Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis

生物信息学分析揭示 FOXM1/BUB1B 信号通路是人类白血病细胞中新骨化素 B 的关键靶点：基于基因网络的微阵列分析

Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells

新骨肉瘤素 B 通过靶向白血病细胞中的 AKT/SKP2/MTH1 轴发挥抗癌作用

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway

血根碱通过产生活性氧和抑制 JAK/STAT 通路介导非小细胞肺癌细胞凋亡