日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An mRNA vaccine encoding the Ebola virus glycoprotein induces high neutralizing antibody titers and provides strong protection against lethal infections in mouse models

编码埃博拉病毒糖蛋白的mRNA疫苗可诱导产生高滴度的中和抗体,并在小鼠模型中提供针对致命感染的强效保护。

Stromberg, Zachary R; Silva, Elvia E; Johnston, Sara C; Johnson, Dylan M; Hall, Dominique; Adjei, Emmanuel F; Altin, John A; Abisoye-Ogunniyan, Abisola; Gollott, Travis; He, Wei; Jones, Iris K A; Kwilas, Steve; Lund, Sean J; Mead, Heather L; Nelson, Georgia A; Ouyang, Lisa; Peters, Sandra K G; Schwedler, Jennifer L; Trecazzi, Caleb Z; Turner, Matthew W; Ye, Chunyan; Bradfute, Steven B; Fischer, Nicholas O; Hooper, Jay W; Ladner, Jason T; Rasley, Amy; Negrete, Oscar A

rVSVΔG-ZEBOV-GP Vaccine Is Highly Immunogenic and Efficacious Across a Wide Dose Range in a Nonhuman Primate EBOV Challenge Model

在非人灵长类动物埃博拉病毒攻击模型中,rVSVΔG-ZEBOV-GP疫苗在较宽的剂量范围内均具有高度免疫原性和有效性。

Shurtleff, Amy C; Trefry, John C; Dubey, Sheri; Sunay, Melek M E; Liu, Kenneth; Chen, Ziqiang; Eichberg, Michael; Silvera, Peter M; Kwilas, Steve A; Hooper, Jay W; Martin, Shannon; Simon, Jakub K; Coller, Beth-Ann G; Monath, Thomas P

Safety and Immunogenicity of an Andes Virus DNA Vaccine by Needle-Free Injection: A Randomized, Controlled Phase 1 Study

无针注射安第斯病毒DNA疫苗的安全性和免疫原性:一项随机、对照的1期研究

Paulsen, Grant C; Frenck, Robert Jr; Tomashek, Kay M; Alarcon, Rodolfo M; Hensel, Elizabeth; Lowe, Ashley; Brocato, Rebecca L; Kwilas, Steve A; Josleyn, Matthew D; Hooper, Jay W

Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle.

在转基因牛中生产针对埃博拉扎伊尔病毒的强效全人源多克隆抗体

Dye John M, Wu Hua, Hooper Jay W, Khurana Surender, Kuehne Ana I, Coyle Elizabeth M, Ortiz Ramon A, Fuentes Sandra, Herbert Andrew S, Golding Hana, Bakken Russell A, Brannan Jennifer M, Kwilas Steve A, Sullivan Eddie J, Luke Thomas C, Smith Gale, Glenn Gregory, Li Wenfang, Ye Ling, Yang Chinglai, Compans Richard W, Tripp Ralph A, Jiao Jin-An

The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial

剂量对VSV埃博拉候选疫苗安全性和免疫原性的影响:一项随机、双盲、安慰剂对照的1/2期试验

Huttner, Angela; Dayer, Julie-Anne; Yerly, Sabine; Combescure, Christophe; Auderset, Floriane; Desmeules, Jules; Eickmann, Markus; Finckh, Axel; Goncalves, Ana Rita; Hooper, Jay W; Kaya, Gürkan; Krähling, Verena; Kwilas, Steve; Lemaître, Barbara; Matthey, Alain; Silvera, Peter; Becker, Stephan; Fast, Patricia E; Moorthy, Vasee; Kieny, Marie Paule; Kaiser, Laurent; Siegrist, Claire-Anne

Antiviral Biologic Produced in DNA Vaccine/Goose Platform Protects Hamsters Against Hantavirus Pulmonary Syndrome When Administered Post-exposure.

在 DNA 疫苗/鹅平台上生产的抗病毒生物制剂,在暴露后给药可保护仓鼠免受汉坦病毒肺综合征的侵害

Haese Nicole, Brocato Rebecca L, Henderson Thomas, Nilles Matthew L, Kwilas Steve A, Josleyn Matthew D, Hammerbeck Christopher D, Schiltz James, Royals Michael, Ballantyne John, Hooper Jay W, Bradley David S

A hantavirus pulmonary syndrome (HPS) DNA vaccine delivered using a spring-powered jet injector elicits a potent neutralizing antibody response in rabbits and nonhuman primates.

使用弹簧动力喷射注射器递送的汉坦病毒肺综合征 (HPS) DNA 疫苗可在兔子和非人灵长类动物中引发强效的中和抗体反应

Kwilas Steve, Kishimori Jennifer M, Josleyn Matthew, Jerke Kurt, Ballantyne John, Royals Michael, Hooper Jay W