日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Non-viral precision T cell receptor replacement for personalized cell therapy

非病毒精准T细胞受体替代用于个性化细胞治疗

Susan P Foy #, Kyle Jacoby #, Daniela A Bota #, Theresa Hunter, Zheng Pan, Eric Stawiski, Yan Ma, William Lu, Songming Peng, Clifford L Wang, Benjamin Yuen, Olivier Dalmas, Katharine Heeringa, Barbara Sennino, Andy Conroy, Michael T Bethune, Ines Mende, William White, Monica Kukreja, Swetha Gunturu,

Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy

PD-1 阻断疗法治疗新抗原靶向 CD8+ T 细胞反应

Cristina Puig-Saus, Barbara Sennino, Songming Peng, Clifford L Wang, Zheng Pan, Benjamin Yuen, Bhamini Purandare, Duo An, Boi B Quach, Diana Nguyen, Huiming Xia, Sameeha Jilani, Kevin Shao, Claire McHugh, John Greer, Phillip Peabody, Saparya Nayak, Jonathan Hoover, Sara Said, Kyle Jacoby, Olivier Da

In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using Alternative Donor Template Delivery Methods

使用替代供体模板递送方法对 HSC 中的 HBB 基因进行同源定向修复的体内结果

Sowmya Pattabhi, Samantha N Lotti, Mason P Berger, Swati Singh, Christopher T Lux, Kyle Jacoby, Calvin Lee, Olivier Negre, Andrew M Scharenberg, David J Rawlings

High Efficiency CRISPR/Cas9-mediated Gene Editing in Primary Human T-cells Using Mutant Adenoviral E4orf6/E1b55k "Helper" Proteins

使用突变腺病毒 E4orf6/E1b55k“辅助”蛋白在原代人类 T 细胞中进行高效 CRISPR/Cas9 介导的基因编辑

Kamila S Gwiazda, Alexandra E Grier, Jaya Sahni, Stephen M Burleigh, Unja Martin, Julia G Yang, Nicholas A Popp, Michelle C Krutein, Iram F Khan, Kyle Jacoby, Michael C Jensen, David J Rawlings, Andrew M Scharenberg

pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences

pEVL:一种用于生成具有扩展编码 Poly(A) 序列的 mRNA IVT 模板的线性质粒

Alexandra E Grier, Stephen Burleigh, Jaya Sahni, Courtnee A Clough, Victoire Cardot, Dongwook C Choe, Michelle C Krutein, David J Rawlings, Michael C Jensen, Andrew M Scharenberg, Kyle Jacoby

Coupling endonucleases with DNA end-processing enzymes to drive gene disruption

将内切酶与 DNA 末端加工酶结合以驱动基因破坏

Michael T Certo, Kamila S Gwiazda, Ryan Kuhar, Blythe Sather, Gabrielle Curinga, Tyler Mandt, Michelle Brault, Abigail R Lambert, Sarah K Baxter, Kyle Jacoby, Byoung Y Ryu, Hans-Peter Kiem, Agnes Gouble, Frederic Paques, David J Rawlings, Andrew M Scharenberg