日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators

使用结合局部抗原和内源性补体调节剂的双特异性抗体进行靶向补体抑制

Haiyu Wang #, Fleur S van de Bovenkamp #, Douwe J Dijkstra, Leoni Abendstein, Nicole V Borggreven, Jos Pool, Rob Zuijderduijn, Christoph Gstöttner, Kyra A Gelderman, Timon Damelang, Gestur Vidarsson, Anna M Blom, Elena Domínguez-Vega, Paul W H I Parren, Thomas H Sharp, Leendert A Trouw

Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation

人类抗 C1q 自身抗体与固相 C1q 特异性结合,增强吞噬作用,但不增强补体活化

Douwe J Dijkstra, Fleur S van de Bovenkamp, Leoni Abendstein, Rob Zuijderduijn, Jos Pool, Cynthia S M Kramer, Linda M Slot, Jan W Drijfhout, Lisanne de Vor, Kyra A Gelderman, Suzan H M Rooijakkers, Arnaud Zaldumbide, Gestur Vidarsson, Thomas H Sharp, Paul W H I Parren, Leendert A Trouw

The NOX2-mediated ROS producing capacity of recipient cells is associated with reduced T cell infiltrate in an experimental model of chronic renal allograft inflammation

受体细胞 NOX2 介导的 ROS 产生能力与慢性肾移植炎症实验模型中 T 细胞浸润减少有关

Marina D Kraaij, Karin M Koekkoek, Kyra A Gelderman, Cees van Kooten

Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species

巨噬细胞对调节性 T 细胞的诱导依赖于活性氧的产生

Marina D Kraaij, Nigel D L Savage, Sandra W van der Kooij, Karin Koekkoek, Jun Wang, J Merlijn van den Berg, Tom H M Ottenhoff, Taco W Kuijpers, Rikard Holmdahl, Cees van Kooten, Kyra A Gelderman